Immunoregulatory effects of Taishan Pinus massoniana pollen polysaccharide on chicks co-infected with avian leukosis virus and Bordetella avium early in ovo |
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| Authors: | Fanxia Guo Cong Xue Cun Wu Xue Zhao Tinghe Qu Xiaohua He Zhongkun Guo Ruiliang Zhu |
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| Institution: | 1. College of Animal Science and Technology, Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agriculture University, Shandong Province 271018, China;2. College of Animal Science and Technology, Shandong Provincial Key Laboratory of Poultry Disease Institute, Shandong Agriculture University, Shandong Province 271018, China |
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| Abstract: | In recent years, co-infection of chicken embryos with immunosuppressive viruses and bacteria occurs with an annually increasing frequency. Consequently, studies on new and safe immunoregulators, especially plant polysaccharides, have become a popular topic in the poultry industry. In the present study, we selected 300 specific pathogen free embryonated eggs, which were injected with subgroup B avian leukosis virus (ALV-B) and Bordetella avium (B. avium) to establish an artificial co-infection model. The chicks that hatched from these co-infected embryonated eggs were treated with Taishan Pinus massoniana pollen polysaccharide (TPPPS). Results indicated that relevant indices in the co-infection group were significantly lower than that in B. avium-only group. Furthermore, pathogenicity of B. avium was exacerbated, with the chicks exhibiting decreased body weights. The TPPPS groups exhibited gradual improvements in immune function and developmental status. Therefore, in terms of improving immunologic function and production performance, TPPPS could be used as immunoregulator for immune responses. |
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| Keywords: | TPPPS Taishan Pinus massoniana pollen polysaccharide ALV avian leukosis virus ALV-B subgroup B avian leukosis virus B avium Bordetella avium IL-2 interleukin-2 IFN-γ interferon-γ LTR lymphocyte transformation rate p27 group-specific antigen ConA concanavalin A |
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