| 饲粮添加锰对3~4月龄獭兔脂肪沉积和脂肪组织脂质代谢的影响 |
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| 引用本文： | 陈晓阳,杨国雨,李凡,张斌,李晨阳,李福昌.饲粮添加锰对3~4月龄獭兔脂肪沉积和脂肪组织脂质代谢的影响[J].动物营养学报,2020(4):1836-1841. |
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| 作者姓名： | 陈晓阳 杨国雨 李凡 张斌 李晨阳 李福昌 |
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| 作者单位： | 山东农业大学动物科技学院;山东省动物生物工程与疾病防治重点实验室 |
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| 基金项目： | 现代农业产业技术体系建设专项(CARS-43-B-1);山东省双一流建设项目(SYL2017YSTD11)。 |
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| 摘 要： | 本试验旨在研究饲粮添加锰对生长獭兔脂肪组织脂质代谢的影响。选用初始体重相近、健康状况良好的3月龄獭兔200只,随机分为5组(每组40个重复,每个重复1只),分别饲喂在基础饲粮中添加0(对照)、5、10、20、40 mg/kg锰(以硫酸锰的形式)的试验饲粮。预试期7 d,正试期29 d。结果表明:1)与对照组相比,饲粮中添加10~20 mg/kg锰显著降低了肩胛脂肪沉积率(P<0.05),饲粮中添加5~40 mg/kg锰显著降低了胃周脂肪沉积率(P<0.05)。饲粮中锰添加水平对肾周脂肪沉积率没有显著影响(P>0.05)。2)饲粮中锰添加水平对肉碱脂酰转移酶2(CPT2)、激素敏感脂酶(HSL)和过氧化物酶体增殖物激活受体β(PPARβ)基因的表达量没有显著影响(P>0.05)。与对照组相比,饲粮中添加20~40 mg/kg锰显著降低了脂肪酸合成酶(FAS)基因的表达量(P<0.05);饲粮中添加20~40 mg/kg锰显著降低了乙酰辅酶A羧化酶(ACC)基因的表达量(P<0.05);饲粮中添加10~40 mg/kg锰显著提高了肉碱脂酰转移酶1(CPT1)基因的表达量(P<0.05);饲粮中添加10~20 mg/kg锰显著提高过氧化物酶体增殖物激活受体α(PPARα)基因的表达量(P<0.05)。综上所述,饲粮中添加锰影响了3~4月龄獭兔的脂肪沉积和脂肪组织脂质代谢,锰添加水平为20 mg/kg时,可以有效促进脂肪组织的氧化分解,抑制脂肪组织的合成,并能降低体脂肪的沉积率。
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| 关 键 词： | 锰 獭兔 脂肪 脂肪代谢 基因表达 |
Effects of Dietary Manganese on Fat Deposition and Lipid Metabolism of Fat Tissue in 3 to 4-Month-Old Rex Rabbits |
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| CHEN Xiaoyang,YANG Gouyu,LI Fan,ZHANG Bin,LI Chenyang,LI Fuchang.Effects of Dietary Manganese on Fat Deposition and Lipid Metabolism of Fat Tissue in 3 to 4-Month-Old Rex Rabbits[J].Acta Zoonutrimenta Sinica,2020(4):1836-1841. |
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| Authors: | CHEN Xiaoyang YANG Gouyu LI Fan ZHANG Bin LI Chenyang LI Fuchang |
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| Institution: | (College of Animal Science and Technology,Shandong Agricultural University,Tai'an 271018,China;Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention,Tai'an 271018,China) |
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| Abstract: | The experiment was conducted to investigate the effects of dietary manganese on lipid metabolism of fat tissue in growing Rex rabbits.Two hundred 3-month-old health Rex rabbits with similar body weight and good health were randomly divided into 5 groups with 40 replicates in each group and 1 rabbit in each replicate.Rabbits in 5 groups were fed a basal diet containing 0(control),5,10,20 and 40 mg/kg manganese(in the form of manganese sulfate),respectively.The trial lasted for 7 days for adaptation,and 29 days for test.The results showed as follows:1)compared with the control group,the addition of 10 to 20 mg/kg manganese significantly reduced the scapular fat deposition rate(P<0.05),and the addition of 5 to 40 mg/kg manganese significantly reduced the perigastric fat deposition rate(P<0.05).The level of manganese in the diet had no effect on the perirenal fat deposition rate(P>0.05).2)The levels of manganese added to the diet had no significant effects on the expression levels of carnitine fatty acyltransferase 2(CPT2),hormone sensitive lipase(HSL)and peroxisome proliferator-activated receptor beta(PPARβ)genes(P>0.05).Compared with the control group,the addition of 20 to 40 mg/kg manganese significantly reduced the expression level of fatty acid synthase(FAS)gene(P<0.05);the addition of 20 to 40 mg/kg manganese significantly reduced the expression of acetyl-CoA carboxylase(ACC)gene(P<0.05);the addition of 10 to 40 mg/kg manganese in the diet significantly increased the expression of carnitine fatty acyltransferase 1(CPT1)gene(P<0.05);the addition of 10 to 20 mg/kg manganese in the diet significantly increased the expression of peroxisome proliferator-activated receptor alpha(PPARα)gene(P<0.05).From what has been discussed above,addition of manganese affects fat deposition and fat metabolism of Rex rabbits.When the level of manganese addition is 20 mg/kg,it can effectively promote the oxidation and decomposition of fat in fat tissue,inhibit fat synthesis in fat tissue,and reduce the deposition rate of body fat. |
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| Keywords: | manganese Rex rabbits fat fat metabolism genetic expression |
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