| 新型蒙脱石抗腹泻的作用机理研究（英文） |
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| 引用本文： | 胡屹屹,苏永腾,何孔旺.新型蒙脱石抗腹泻的作用机理研究（英文）[J].农业科学与技术,2013(12):1810-1812,1851. |
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| 作者姓名： | 胡屹屹 苏永腾 何孔旺 |
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| 作者单位： | [1]江苏省农业科学院兽医研究所农业部兽用生物制品工程技术重点实验室国家兽用生物制品工程技术研究中心,江苏南京210014 [2]南京禾嘉牧业有限公司,江苏南京211135 |
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| 基金项目： | 江苏省农业科技自主创新基金[CX（13）5030]. |
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| 摘 要： | 目的]拟探讨新型蒙脱石防治仔猪腹泻的作用机理。方法]选取30头健康＂杜×大×长＂三元杂交断奶仔猪,随机分为5组。分别饲喂基础日粮、基础日粮＋1 g/kg新型蒙脱石、基础日粮＋3 g/kg新型蒙脱石、基础日粮＋5g/kg新型蒙脱石和基础日粮＋3 g/kg微生态制剂。4周后动物前腔静脉采血,检测血清中TFF3、NO和SOD的含量。结果]与空白对照组相比,新型蒙脱石高剂量组动物血清中TFF3水平极显著升高,NO水平极显著降低,SOD水平显著升高;新型蒙脱石中剂量组动物血清中TFF3水平显著升高,NO水平显著降低。结论]新型蒙脱石抗断奶仔猪腹泻的作用机理可能与上调机体TFF3和SOD水平,下调NO含量有关。
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| 关 键 词： | 蒙脱石 腹泻 小肠三叶因子 一氧化氮 超氧化物歧化酶 |
Study on the Mechanism of Innovative Montmorillonite for Diarrhea Treatment |
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| Yiyi HU,Yongteng SU,Kongwang HE.Study on the Mechanism of Innovative Montmorillonite for Diarrhea Treatment[J].Agricultural Science ＆ Technology,2013(12):1810-1812,1851. |
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| Authors: | Yiyi HU Yongteng SU Kongwang HE |
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| Institution: | 1. Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences / Key Laboratory of Veterinary Biological Engineer- ing and Technology, Ministry of Agriculture / National Center for Engineering Research of Veterinary Bio-products, Nanjing 210014, China 2. Nanjing Higet Animal Sci. ＆ Tech. Co., Ltd., Nanjing 211135, China |
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| Abstract: | Objective] This study aimed to investigate the mechanism of innovative montmorillonite for diarrhea treatment. Method] Thirty healthy weanling piglets （Duroc x Landrace x Yorkshire） were randomly divided into five groups and fed with basal diet, basal diet ＋ 1 g/kg innovative montmorillonite, basal diet ＋ 3 g/kg innovative montmorillonite, basal diet ＋ 5 g/kg innovative montmorillonite and basal diet ＋ 3 g/kg Bacillus subtilis microecologic agent, respectively. After four weeks, blood samples were collected via precaval vein, to detect the content of TFF3, NO and SOD in serum by ELISA kits. Result] Compared with blank control group, the content of TFF3, NO and SOD in high-dose innovative montmorillonite group was extremely significantly increased, extremely significantly reduced and significantly in- creased, respectively; the content of TFF3 and NO in middle-dose innovative mont- morillonite group was significantly increased and significantly reduced, respectively. Conclusion] Innovative montmorillonite may exert beneficial therapeutic actions on diarrhea by increasing TFF3 and SOD levels and decreasing NO level. |
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| Keywords: | Montmorillonite Diarrhea TFF3 NO SOD |
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