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Traces of human migrations in Helicobacter pylori populations
Authors:Falush Daniel  Wirth Thierry  Linz Bodo  Pritchard Jonathan K  Stephens Matthew  Kidd Mark  Blaser Martin J  Graham David Y  Vacher Sylvie  Perez-Perez Guillermo I  Yamaoka Yoshio  Mégraud Francis  Otto Kristina  Reichard Ulrike  Katzowitsch Elena  Wang Xiaoyan  Achtman Mark  Suerbaum Sebastian
Institution:Department of Molecular Biology, Max-Planck Institut für Infektionsbiologie, 10117 Berlin, Germany.
Abstract:Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive their gene pools from ancestral populations that arose in Africa, Central Asia, and East Asia. Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade.
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