First-time detection of mycobacterium species from goats in Ethiopia |
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| Authors: | Hiko Adem Agga Getahun Ejeta |
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| Institution: | (1) Faculty of Veterinary Medicine, Department of Epidemiology, Microbiology and Veterinary Public Health, Haramaya University, Haramaya, Ethiopia;(2) Faculty of Veterinary Medicine, Department of Microbiology and Veterinary Public Health, Addis Ababa University, P.O. Box 34, Bishoftu, Ethiopia;(3) Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA; |
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| Abstract: | Tuberculosis (TB) is an important zoonosis affecting a wide range of hosts. An abattoir study was conducted on 1,536 randomly
selected male goats slaughtered at Modjo Modern Export Abattoir to determine the prevalence of tuberculosis in slaughtered
goats. Carcasses and organs of all the study animals were first examined by routine meat inspection followed by detailed meat
inspection. Samples from tuberculous lesions were cultured for mycobacterial isolation and identification. Histopathology
was done on 31 samples with tuberculous lesions. Detailed meat inspection detected 65 (4.2%; 95% confidence interval (CI) = 3.3–5.4%)
tuberculous lesions. From these, 20 (30.8%) samples were confirmed mycobacterium positive on culture, out of which 18 were
Mycobacterium bovis and two were Mycobacterium tuberculosis. Routine meat inspection failed to detect tuberculous lesions in 23% of carcasses with TB lesions detected by detailed examination.
However, no statistically significant difference was observed between both methods in detecting tuberculous lesions (Kappa = 0.87).
Origin and age of the goats did not statistically affect the disease prevalence (P > 0.05). Histopathologic lesions were observed in 21 samples (68%; 95% CI = 50.1–81.4%) out of the 31 carcasses with gross
tuberculous lesions examined by histopathology. Eighteen (58%) tuberculous samples positive for histopathology were also culture
positive. The sensitivity and specificity of histopathology were 90% (95% CI = 76.9–100%) and 72.7% (95% CI = 46.4–99%), respectively,
using culture as a reference test. To the best of our knowledge, this is the first report of caprine tuberculosis from Ethiopia.
Further studies are required at the farm level to determine the prevalence of tuberculosis in the general goat population. |
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