| 猪β防御素-1的研究进展 |
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| 引用本文： | 孟虹艳,李培锋,朱建国,华修国,杨志彪.猪β防御素-1的研究进展[J].中国畜牧兽医,2007,34(9):50-52. |
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| 作者姓名： | 孟虹艳 李培锋 朱建国 华修国 杨志彪 |
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| 作者单位： | 1.内蒙古农业大学动物科学与医学学院,呼和浩特 010018；2 上海交通大学农业与生物学院,上海 200240 |
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| 摘 要： | 猪β防御素-1 (porcine β-defensin 1,PBD-1)是广泛分布于猪消化道、呼吸道、肝肾等多种组织细胞内的一类活性多肽,在猪防御系统中有着重要的作用,大量研究结果证明PBD-1具有独特的作用机制,几乎无耐药性, 已引起各国研究者的日益重视。目前对PBD-1科研工作在不断深入,可以相信PBD-1将在动物养殖、疾病预防和提高畜产品品质方面发挥重要作用。作者就PBD-1的分布、分子结构、抗菌作用机制和基因表达调控研究进展作一综述。
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| 关 键 词： | 猪β防御素-1 抗菌肽 研究进展 |
| 文章编号： | 1671-7236（2007）09-0050-03 |
| 修稿时间： | 2007-04-12 |
Advances in the Research of Porcine β Defensin-1 |
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| MENG Hong-yan,LI Pei-feng,ZHU Jian-guo,HUA Xiu-guo,YANG Zhi-biao.Advances in the Research of Porcine β Defensin-1[J].China Animal Husbandry & Veterinary Medicine,2007,34(9):50-52. |
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| Authors: | MENG Hong-yan LI Pei-feng ZHU Jian-guo HUA Xiu-guo YANG Zhi-biao |
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| Institution: | 1.Inner Mongolia Agriculture University College of Animal Science and Animal Medicine, Huhhot 010018,China; 2.Shanghai Jiao Tong University College of Agriculture and Biology, Shanghai 200240,China |
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| Abstract: | PBD-1 is an antibacterial peptide that plays an important role in defense system of porcine.which have high expression in porcine respiratory and digestive tracts and also in liver,kidney and more tissue cells.lots of researches prove PBD-1 has distinctive function mechanism and hardly no-endurance to pill.So more researchers of every country have pay attention increasingly to it.now the research work for PBD-1 is more deeply.PBD-1 plays a important role in animal breeding,illness prevention and progression of quality of livestock good.Here we report PBD-1's research advancement on PBD-1 distribution,properties,molecular structure,mechanisms of antimicrobial activity and gene expression and regulation. |
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| Keywords: | PBD-1 antimicrobial peptide research advancement |
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