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| 应用禽痘病毒表达载体研制重组疫苗的研究进展 | |
| 引用本文： | 乔传玲,袁远,于康震.应用禽痘病毒表达载体研制重组疫苗的研究进展[J].动物医学进展,2002,23(1):34-37. |
| 作者姓名： | 乔传玲 袁远 于康震 |
| 作者单位： | 1. 中国农业科学院哈尔滨兽医研究所兽医生物技术国家重点实验室,黑龙江,哈尔滨,150001 2. 河南农业大学牧医工程学院,河南郑州,450002 3. 中国农业部畜牧兽医局,北京,100026 |
| 摘 要： | 禽痘病毒是继痘苗病毒之后又一种重要的动物病毒表达载体，它具有严格的宿主特异性和生物安全性，从而使它成为禽类病原基因工程活载体疫苗研制过程中的一种应用极为广泛的工具；同时它在其它哺乳动物乃至人类病原基因的表达方面也显示了独特的优越性及广阔的开发和应用前景，本文对禽痘病毒作为表达载体的研究进展，应用前景及目前存在的问题作了综述。 |
| 关 键 词： | 禽痘病毒 病毒表达载体 重组疫苗 安全性 应用前景 基因工程疫苗 |
| 文章编号： | 1007-5038(2002)01-0034-04 |
| 修稿时间： | 2000年11月13 |
Progress in Production of Recombinant Vaccine Based on Fowlpox Virus Vector |
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| QIAN Chuan-ling,YUAN Yuan,YU Kang-zhen.Progress in Production of Recombinant Vaccine Based on Fowlpox Virus Vector[J].Progress In Veterinary Medicine,2002,23(1):34-37. | |
| Authors: | QIAN Chuan-ling YUAN Yuan YU Kang-zhen |
| Institution: | QIAN Chuan-ling1,YUAN Yuan2,YU Kang-zhen3 |
| Abstract: | Fowlpox virus was an expressing vector based on live -virus, followed b y vaccinia virus. It was host-specific to avian species, which made it more sui t able than other vector for use as poultry vaccine vectors because of no risk of FPV outside the extend target species. Meanwhile, fowlpox virus has also become an important vector to successfully express the protective immunogen genes from several mammals- as well as human-origin viruses. So the research development s, application prospects and problems remained in this field were reviewed in the p resent paper. |
| Keywords: | fowlpox virus recombinant vector |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |