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Molecular biology and biotechnology for reduction of Fusarium mycotoxin contamination |
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| Authors: | Makoto Kimura Naoko Takahashi-Ando Takumi Nishiuchi Takeshi Tokai Makoto Fujimura Hiroshi Hamamoto Isamu Yamaguchi |
| Institution: | a Plant and Microbial Metabolic Engineering Research Unit, Discovery Research Institute (DRI), RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan b Laboratory for Remediation Research, Plant Science Center (PSC1), RIKEN, 1-7-22 Suehiro, Yokohama, Kanagawa 230-0045, Japan c Environmental Molecular Biology Laboratory, Discovery Research Institute (DRI), RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan d Division of Functional Genomics, Advanced Science Research Center, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-0934, Japan e Department of Life Science, Toyo University, 1-1-1 Izumino, Itakura, Gunma 374-0193, Japan f Laboratory for Adaptation and Resistance, Plant Science Center (PSC1), RIKEN, 1-7-22 Suehiro, Yokohama, Kanagawa 230-0045, Japan |
| Abstract: | Fusarium head blight (FHB) is a devastating disease of important cereal crops resulting in significant yield loss and mycotoxin contamination. Persistent outbreaks of FHB in Europe and North America have led to various efforts to understand the mechanisms of resistance to this disease and mycotoxin biosynthesis. In this minireview, we summarize basic and applied studies conducted in our laboratories into reducing mycotoxin contamination in FHB. |
| Keywords: | Acetyltransferase Detoxification Deoxynivalenol (DON) Estrogenic mycotoxin Fusarium graminearum Genetically modified organisms (GMO) Lactonohydrolase Small grain cereal crops Trichothecene biosynthesis Zearalenone degradation |
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