| 优化超高效液相色谱法对鸡蛋中氟喹诺酮类药物残留的检测 |
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| 引用本文： | 李宁,林小莉,董艳峰.优化超高效液相色谱法对鸡蛋中氟喹诺酮类药物残留的检测[J].黑龙江农业科学,2014(3):107-110. |
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| 作者姓名： | 李宁 林小莉 董艳峰 |
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| 作者单位： | 哈尔滨市兽药饲料监察所,黑龙江哈尔滨150010 |
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| 摘 要： | 为制定畜产品中沙星类药物残留高效实用的检测标准,建立一种测定鸡蛋中4种氟喹诺酮类药物(环丙沙星、恩诺沙星、沙拉沙星、达氟沙星)残留的超高效液相色谱检测方法。结果表明:4种氟喹诺酮类药物峰面积与质量浓度呈良好的线性关系,R2均大于0.999 8。环丙沙星、恩诺沙星、沙拉沙星的线性范围为0~500μg·L-1,达氟沙星的线性范围为0~100μg·L-1。鸡蛋样品中氟喹诺酮类药物的回收率为78.9%~95.3%,相对标准偏差为5.5%~8.7%,检出限为10μg·kg-1。
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| 关 键 词： | 环丙沙星 恩诺沙星 达氟沙星 沙拉沙星 超高效液相色谱 鸡蛋 |
Detection of Quinolones Residues in Egg by UPLC Method |
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| LI Ning,LIN Xiao-li,DONG Yan-feng.Detection of Quinolones Residues in Egg by UPLC Method[J].Heilongjiang Agricultural Science,2014(3):107-110. |
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| Authors: | LI Ning LIN Xiao-li DONG Yan-feng |
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| Institution: | (Institute of Veterinary Drug and Food Control in Harbin, Harbin, Heilongjiang 150010) |
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| Abstract: | In order to establish efficient and practical testing standard for animal products of quinolones（cipro- floxacins,enrofloxacin,danofloxacin,sarafloxacin） residues in egg, the quinolones residues in egg were deter- mined by UPLC. The results showed that there were good linear correlations between the peak areas and con- centrations of four fluoroquinolones,the R2 were above 0. 999 8. The dynamic linear range was 0-500 μg·L^-1 for eiprofloxaeins,enrofloxacin and sarafloxacin,0-100 μg·L^-1 for danofloxacin. The average recoveries of the four fluoroquinolones in eggs ranged from 78.9 % - 95.3 % and relative standard deviations was 5. 5 - 8.7% ,the detection limit was 10μg.kg. |
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| Keywords: | ciprofloxacins enroffoxacin danofloxacin sarafloxacin ultra performance liquid ehronmtography egg |
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