| 蜂胶对糖尿病大鼠肾脏的影响 |
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| 引用本文： | 胡福良,玄红专,詹耀锋.蜂胶对糖尿病大鼠肾脏的影响[J].蜜蜂杂志,2004(2):3-4. |
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| 作者姓名： | 胡福良 玄红专 詹耀锋 |
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| 作者单位： | 浙江大学动物科学学院,浙江,杭州,310029 |
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| 摘 要： | 将复制糖尿病模型的72只SD大鼠随机分为模型组、蜂胶水提液低剂量组(WSP1),蜂胶水提液高剂量组(WSP2)、蜂胶醇提液低剂量组(EEP1)、蜂胶醇提液高剂量组(EEP2)和阳性对照组,另取12只为正常组.除正常组和模型组外,各组分别给予不同的试验药物.给药7周后,抽血测生化指标,同时取肾脏,计算肾脏/体重.结果发现蜂胶能降低糖尿病大鼠的尿酸、尿素、肌酐水平,并且蜂胶给药组大鼠的肾重/体重均比模型组低,表明蜂胶对糖尿病机体内的肾脏组织具有保护作用.
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| 关 键 词： | 蜂胶 糖尿病 肾脏 尿酸 尿素 肌酐 |
| 文章编号： | 1003-9139(2004)02-0003-02 |
| 修稿时间： | 2003年12月8日 |
Effects of propolis on kidney in diabetes mellitus rats |
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| HU Fu-liang,XUAN Hong-zhuan,ZHAN Yao-feng.Effects of propolis on kidney in diabetes mellitus rats[J].Journal of Bee,2004(2):3-4. |
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| Authors: | HU Fu-liang XUAN Hong-zhuan ZHAN Yao-feng |
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| Abstract: | diabetic mellitus SD rats were randomly divided into 6 groups, an d given intragastrically(1)sterile saline(model control group),(2)propolis solut ions extracted by water(low dose), (3) propolis solutions extracted by water ( h igh dose), (4) propolis solutions extracted by ethanol (low dose), (5) propolis solutions extracted by ethanol (high dose), or (6) acarbose (positive control g roup) respectively and treated twice daily continuously for 7 weeks. The serum levels of uric acid , urea and creatinine were determined and comparision betwee n the groups ,and the ratio between kidney weight and body weight was also deter mined . The results showed that propolis could decrease the serum level of uric acid ,urea and creatinine, and could decrease the ratio between kidney weight an d body weight. The results indicate that propolis could protect kidney in diabe tic mellitus |
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| Keywords: | propolis diabetic mellitus kidney uric acid urea creatinine |
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