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新城疫La Sota疫苗对山东分离株的免疫保护试验
引用本文:王友令,徐怀英,李莉,秦卓明.新城疫La Sota疫苗对山东分离株的免疫保护试验[J].中国家禽,2007,29(19):19-21.
作者姓名:王友令  徐怀英  李莉  秦卓明
作者单位:山东省农业科学院家禽研究所,山东济南,250100
摘    要:用标准疫苗株La Sota活疫苗在隔离器中接种SPF鸡,进行免疫保护试验.免疫后,每7 d采血监测NDV抗体,免疫后2周,利用经过鉴定的新城疫病毒(NDV)潍坊毒SGM01、昌乐毒SCL03、东营毒HY、日照毒SRZ03、莘县毒SSX03和标准强度F48E9分别进行攻毒试验,同时设SPF鸡对照.每天观察,及时剖检发病鸡,检查鸡群病变,确定疫苗的保护性.结果表明,La Sota疫苗能对除SGM01和HY以外的病毒攻击的SPF鸡提供较好的保护.

关 键 词:新城疫  La  Sota疫苗  保护  SPF鸡
修稿时间:2007年6月19日

Immune Protection of La Sota Vaccine against Newcastle Disease Viruses Shandong Isolates
Wang Youling,Xu Huaiying,Li Li,Qin Zhuoming.Immune Protection of La Sota Vaccine against Newcastle Disease Viruses Shandong Isolates[J].China Poultry,2007,29(19):19-21.
Authors:Wang Youling  Xu Huaiying  Li Li  Qin Zhuoming
Abstract:Six groups of SPF chickens were immunized with Newcastle disease virus(NDV) La Sota strain vaccine. To evaluate the efficacy of this vaccine against NDV isolates challenge,NDV antibody titers were detected every seven days and challenged chickens with Shandong isolates and standard F48E9 strain after two weeks. Autopsy was performed to confirmed that the sickness and dead chickens were infected with ND. The experiment results showed that the La Sota vaccine could provide a better protection for SPF chickens challenged by NDV isolates and F48E9 strain but SGM01 isolate and HY isolate.
Keywords:Newcastle disease  La Sota strain vaccine  protection  SPF chicken
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