Acute toxicity of emamectin benzoate (SLICE™) in fish feed to American lobster, Homarus americanus |
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| Authors: | Les E Burridge Natalie Hamilton Susan L Waddy Katsuji Haya Sarah M Mercer Roy Greenhalgh Ronald Tauber Steven V Radecki Louis S Crouch Peter G Wislocki & Richard G Endris |
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| Institution: | Fisheries and Oceans Canada, Biological Station, St Andrews, NB, Canada; Enviro-Test Laboratories/Xenos Division, Nepean, Ont., Canada; Statistical Consultant, Fort Collins, CO, USA; Schering-Plough Research Institute, Lafayette, NJ, USA; Schering-Plough Animal Health Corporation, Union, NJ, USA |
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| Abstract: | SLICE? (active ingredient 0.2% emamectin benzoate (EMB)), a feed premix developed by Schering‐Plough Animal Health for the control of sea lice on cultured salmonids, is registered for use in several countries and is being prescribed on an emergency basis in Canada and the United States. The concentration of EMB in feed administered to farmed salmon ranges from 1 to 25 μg g?1. To determine the acute toxicity of the compound to juvenile and adult American lobster (Homarus americanus), commercial salmon feed was coated with SLICE? at a range of concentrations and provided to the animals for 7 d in the laboratory. The LC50 is estimated to be 644 μg g?1 (95% CI=428, 1275) for adult lobsters and >589 μg g?1 for stage V and VI juvenile lobsters. The consumption of medicated pellets by adult lobsters decreased significantly with increasing concentration of EMB. Adult lobsters that died during the study had a significantly greater concentration of emamectin B1a in their muscle tissue than those that survived. These results support the conclusion that salmon feed medicated with EMB at the concentrations used by the aquaculture industry is unlikely to pose an acute lethal threat to adult and small juvenile American lobsters. |
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| Keywords: | emamectin benzoate Homarus americanus LC50 toxicity lobster SLICE? |
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