| 动物源细菌质粒介导的氟喹诺酮药物耐药性研究进展 |
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| 引用本文： | 连明香,李德喜,李新生,杜向党.动物源细菌质粒介导的氟喹诺酮药物耐药性研究进展[J].江西农业学报,2009,21(9):155-157. |
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| 作者姓名： | 连明香 李德喜 李新生 杜向党 |
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| 作者单位： | 河南农业大学,牧医工程学院,河南,郑州,450002 |
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| 基金项目： | 河南省高等学校青年骨干教师资助计划 |
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| 摘 要： | 质粒介导的氟喹诺酮药物耐药机制可加重许多革兰氏阴性细菌对氟喹诺酮药物耐药性,并可在细菌之间进行水平传播,现已成为临床用药的重大难题。综述了质粒介导的氟喹诺酮药物耐药性的发现过程、耐药机制、兽医临床分布、遗传背景及扩散等,以期为该类耐药机制的研究提供参考。
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| 关 键 词： | 动物源 质粒 氟喹诺酮类 耐药性 |
Research Advance in Plasmid-mediated Fluoroquinolones Resistance among Bacteria Originated from Animals |
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| LIAN Ming-xiang,LI De-xi,LI Xin-sheng,DU Xiang-dang.Research Advance in Plasmid-mediated Fluoroquinolones Resistance among Bacteria Originated from Animals[J].Acta Agriculturae Jiangxi,2009,21(9):155-157. |
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| Authors: | LIAN Ming-xiang LI De-xi LI Xin-sheng DU Xiang-dang |
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| Abstract: | Plasmid-mediated fluoroquinolones resistant mechanism can aggravate the resistance of many Gram-negative bacteria to fluoroquinolones,which can also occur via horizontal dissemination.This will ultimately cause the difficulties in clinical treatment.This paper summarized the discovery process,resistant mechanism,veterinary clinic distribution,genetic background and dissemination of plasmid-mediated fluoroquinolones resistance,in order to cause the concern of the related scholars in the fields. |
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| Keywords: | Animal origin Plasmid Fluoroquinolones Resistance |
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