Concurrent T cell leukaemia and equine multinodular pulmonary fibrosis in a Hanoverian Warmblood mare |
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| Authors: | B Schwarz A Gruber V Benetka B Rütgen I Schwendenwein E Leidinger R van den Hoven |
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| Institution: | 1. Equine Clinic, Section Internal Medicine, University of Veterinary Medicine Vienna, Austria;2. Institute of Pathology and Forensic Veterinary Medicine, University of Veterinary Medicine Vienna, Austria;3. Clinical Virology, University of Veterinary Medicine Vienna, Austria;4. Clinical Immunology, University of Veterinary Medicine Vienna, Austria;5. Central Laboratory, University of Veterinary Medicine Vienna;6. Invitro Diagnostic Laboratory, Vienna, Austria |
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| Abstract: | Equine multinodular pulmonary fibrosis (EMPF) and primary leukaemia are uncommon diseases in horses. This case report describes a horse with both diseases which might be linked via the equine γ‐herpesvirus EHV‐5. In man Epstein Barr Virus (EBV), also a γ‐herpesvirus, is associated with idiopathic pulmonary fibrosis as is EHV‐5 with EMPF. Furthermore, EBV is also associated with lymphoproliferative disease. Similarly in horses, primary leukaemia might be associated with EHV‐5. This is the first report associating EHV‐5 with primary leukaemia in horses. |
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| Keywords: | horse EMPF leukaemia γ ‐herpesvirus immunosuppression |
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