| H5N1流感病毒感染恒河猴短期和恢复期病理学观察 |
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| 引用本文： | 闵凡贵,张钰,赵维波,王静,刘香梅,刘忠华,谭文雅,黄韧.H5N1流感病毒感染恒河猴短期和恢复期病理学观察[J].动物医学进展,2006,27(6):58-60. |
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| 作者姓名： | 闵凡贵 张钰 赵维波 王静 刘香梅 刘忠华 谭文雅 黄韧 |
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| 作者单位： | 广东省实验动物监测所,广东广州510260 |
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| 基金项目： | 广东省科技厅农业科技攻关项目 |
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| 摘 要： | 为观察恒河猴在感染H5N1流感病毒后短期和恢复期的病理学变化,利用1株鹅源H5N1流感病毒环甲膜穿刺接种恒河猴。感染后短期内恒河猴产生了典型的肺炎和肺外器官不同程度的损伤,3个月后,恒河猴从病理上表现恢复。病理检查结果表明,H5N1流感病毒对恒河猴的感染是一种急性的呼吸道综合征,并伴有多器官功能不全的症状,随着感染时间的延长,可通过自身免疫调节恢复正常。
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| 关 键 词： | H5N1流感病毒 环甲膜穿刺接种 病理变化 |
| 文章编号： | 1007-5038（2006）06-0058-03 |
| 收稿时间： | 2006-02-23 |
Pathologic Changes of Rhesus Macaques Infected with Avian influenza virus (H5N1) in a Short Period and Recovery Period Post-infection |
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| MIN Fan-gui,ZHANG Yu,ZHAO Wei-bo,WANG Jing,LIU Xiang-mei,LIU Zhong-hua,TAN Wen-ya,HUANG Ren.Pathologic Changes of Rhesus Macaques Infected with Avian influenza virus (H5N1) in a Short Period and Recovery Period Post-infection[J].Progress In Veterinary Medicine,2006,27(6):58-60. |
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| Authors: | MIN Fan-gui ZHANG Yu ZHAO Wei-bo WANG Jing LIU Xiang-mei LIU Zhong-hua TAN Wen-ya HUANG Ren |
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| Institution: | Guangdong Laboratory Animal Monitoring Institute, Guangzhou, Guangdong, 510260, China |
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| Abstract: | To observe pathologic changes of Avian influenza virus(H5N1) to rhesus macaques in a short period and recovery period post-infection.Rhesus macaques were infected by the inoculation of thyrocricoid puncture.The rhesus macaque had severe disease in a short period and began to recover by three months post-infection.The infection of Avian influenza virus(H5N1) caused acute respiratory distress syndrome(ARDS) firstly,and then ARDS may upgrade to multiple organ dysfunction syndrome(MODS).The lesions could recover by self little by little. |
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| Keywords: | Avian influenza virus(H5N1) thyrocricoid puncture pathologic changes |
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