| 甘薯糖蛋白对小鼠血脂水平的影响 |
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| 作者姓名： | 华 松 贾战生 武 浩 李 蓉 蒋亚莉 张 涌 |
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| 作者单位： | 西北农林科技大学动物科技学院 陕西杨凌712100(华松，武浩，李蓉，张涌)，第四军医大学唐都医院 陕西西安710000(贾战生)，西北农林科技大学校医院 陕西杨凌712100(蒋亚莉) |
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| 基金项目： | 国家自然科学基金资助项目“用人移植核胚胎干细胞建立个体化肝细胞的研究”(30371282)。 |
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| 摘 要： | 为了研究甘薯糖蛋白对小鼠血脂水平的影响。先用含8.0%猪油的高脂鼠料诱导小鼠成为高脂血,再将其平均分为四组,一组用普通鼠料饲养作为对照,其他三组分别用含0.5%、1.0%及1.5%甘薯糖蛋白的鼠料饲养,在第15天和第30天对每只小鼠采血,用全自动生化分析仪测定其中的甘油三酯及血清胆固醇的浓度。结果发现用含1.0%甘薯糖蛋白的鼠料饲养15d就能明显降低高脂血模型小鼠血液中的血清总胆固醇水平,继续饲养30d能显著降低其中的甘油三酯水平;如果用含1.5%甘薯糖蛋白的鼠料饲喂,则只需15d就能同时降低两者的水平。因此甘薯糖蛋白具有显著降低高脂血模型小鼠血脂的作用。
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| 关 键 词： | 甘薯糖蛋白 高脂血 小鼠 |
Therapeutic Effects of SPG on Serum Lipid Levels in Mice |
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| Authors: | Hua Song Jia Zhansheng Wu Hao Li Rong Jiang Yali Zhang Yong |
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| Abstract: | In order to study the effects of sweet-potato glycoprotein (SPG)on the serum lipid levels in mice, a group of mice models of hyperlipidemia were set up by basic diet and 8.0% lard , then divided into 4 groups equally, the first group, which was control group , were fed on basic diet , other three groups were fed on basic diet with 0.5%, 1.0% and 1.5% SPG respectively. The concentrations of serum lipid were detected by full automatic biochemical analysis instrument every other 15 days. The results showed that basic diet containing 1.0% SPG could obviously reduce the concentration of serum total cholesterol(TC) within 15 days, and the concentration of triglycercles(TG) within 30 days, besides these,the basic diet containing 1.5% SPG could lower the both TG and TC levels significantly. So SPG has effects on decreasing the blood lipids concentration. |
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| Keywords: | Sweet-potato glycoprotein Hyperlipidemia Mice |
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