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Redox profile in liver of Leporinus macrocephalus exposed to different dissolved oxygen levels |
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| Authors: | Riffel A P K Garcia L O Finamor I A Saccol E M H Meira M Kolberg C Horst A Partata W Llesuy S Baldisserotto B Pavanato M A |
| Institution: | 1. Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, Santa Maria, Brazil 4. Instituto de Oceanografia, Universidade Federal do Rio Grande, Rio Grande, Brazil 5. Departamento de Morfologia, Universidade Federal de Santa Maria, Santa Maria, Brazil 6. Departamento de Fisiologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil 2. Departamento de Fisiologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil 3. Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Buenos Aires, Argentina |
| Abstract: | Aquatic organisms are continuously exposed to environmental variations, which can lead to physiological and biochemical alterations. Leporinus macrocephalus, known as piavu?u, is a migratory species that may be exposed to variations in dissolved oxygen levels. Studies evaluating oxidative changes undergone by this species in these conditions are scarce. Therefore, this investigation aimed at evaluating oxidative alterations in L. macrocephalus exposed to different oxygen levels for 96?h: 6.12?±?0.18, 3.99?±?0.17, 3.22?±?0.17, 2.47?±?0.30 and 0.710?±?0.07?mg?L(-1). At the end of the experimental period, fish were euthanized and livers used to determine lipid hydroperoxides, thiobarbituric acid reactive substances, catalase, glutathione-S-transferase, superoxide dismutase and thiol groups, which are an indirect measure of reduced glutathione. Results indicated a decrease in the studied parameters in hypoxic situations, suggesting a possible metabolic depression. |
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