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Chordoma of the thoracic vertebrae in a Bengal tiger (Panthera tigris tigris)
Authors:Mizuki KURAMOCHI  Takeshi IZAWA  Mayuka HORI  Kayo KUSUDA  Junichiro SHIMIZU  Toshie ISERI  Hideo AKIYOSHI  Fumihito OHASHI  Mitsuru KUWAMURA  Jyoji YAMATE
Institution:1)Veterinary Pathology, Osaka Prefecture University, 1–58 Rinku-Ourai-Kita, Izumisano City, Osaka 598–8531, Japan;2)Misaki Koen, 3990 Tannowa, Misaki-Cho, Osaka 599–0301, Japan;3)Veterinary Medical Center, Osaka Prefecture University, 1–58 Rinku-Ourai-Kita, Izumisano City, Osaka 598–8531, Japan
Abstract:A 19-year-old female Bengal tiger (Panthera tigris tigris) was presented with hind limb weakness, ataxia and respiratory distress. Computed tomography revealed a mass between the left side of the T7 vertebra and the base of the left 7th rib. The tiger then died, and necropsy was performed. Grossly, the vertebral mass was 6 × 5.7 × 3 cm, and invaded the adjacent vertebral bone and compressed the T7 spinal cord. Histologically, the mass was composed of large, clear, vacuolated and polygonal cells with osteochondral matrix. Cellular and nuclear atypia were moderate. The vacuolated cells stained positively for cytokeratin and vimentin and negatively for S-100. Based on these findings, the present case was diagnosed as a vertebral chordoma; the first report in a tiger.
Keywords:chordoma  neurological symptom  tiger  vertebral tumor
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