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Scintigraphic diagnosis of primary hepatocellular carcinoma in the woodchuck (Marmota monax)
Authors:F A Kallfelz  W E Hornbuckle  H J Harvey  R J Wallace  L G Potkewitz  L Roth  B C Tennant
Abstract:Hepatic imaging with 99mTc-sulfur colloid was used to diagnose primary hepatocellular carcinoma (PHC) in woodchucks infected with woodchuck hepatitis virus (WHV). Based on imaging results, 6 of 12 WHV-infected woodchucks had space-occupying hepatic lesions, and all 6 had PHC. Of the remaining woodchucks, 2 did not have PHC, 2 had discrete tumors (less than 1 cm diameter), 1 had miliary small tumors, and 1 had tumors located near the great vessels. Hepatic imaging was a valuable technique for diagnosis of PHC in WHV-infected woodchucks.
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