Further development of P. multocida vaccines for swine |
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| Authors: | D Schimmel |
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| Institution: | Institut für bakterielle Tierseuchenforschung Jena-Zw?tzen, Akademie der Landwirtschaftswissenschaften. |
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| Abstract: | 149 strains with antigen fractions of both A and D type could be found out of 446 P. multocida field strains of porcine origin. Most of them are producing the dermonecrotizing toxin. These A/D strains proved to be virulent in mice and piglets as well. In mice, the vaccination with one of the most virulent and immunogenic A/D strains, inactivated and A1(OH)3 adsorbed caused an immunity against challenge infections with P. multocida of types A, D and A/D. This effect could be confirmed on SPF piglets. |
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