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Blackgram fiber (Phaseolus mungo): Mechanism of hypoglycemic action
Authors:Boby  RG  Leelamma  S
Institution:(1) Department of Biochemistry, University of Kerala, Kariavattom Thiruvananthapuram, 695 581, India
Abstract:The effect of the administration of blackgram fiber (Phaseolusmungo) on the metabolism of carbohydrates was studied in rats fed 30%NDF (neutral detergent fiber) diet. The experimental group showed a significant increase in liverglycogen level and a significant decrease in blood glucose. Significantincreases in the activities of glycogen phosphorylase, hexokinase, fructose-1,6-diphosphatase, glucose-6-phosphate dehydrogenase and isocitratedehydrogenase were observed in the experimental group. The activities ofphosphoglucomutase and glucose-6-phosphatase were significantly lower inrats fed the fiber diet. The study showed that blackgram fiber exhibitssignificant hypoglycemic action in experimental animals.
Keywords:Blackgram  Fiber  Gluconeogenesis  Glycogen  Glycogenesis  Glycolysis  Hexokinase  Phosphoglucomutase
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