| 茶多酚调控机制及其对奶牛乳房炎的干预作用 |
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| 引用本文： | 茶多酚调控机制及其对奶牛乳房炎的干预作用.茶多酚调控机制及其对奶牛乳房炎的干预作用[J].畜牧与饲料科学,2023,44(1):60-63. |
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| 作者姓名： | 茶多酚调控机制及其对奶牛乳房炎的干预作用 |
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| 作者单位： | 1.内蒙古自治区农牧业科学院动物营养与饲料研究所,内蒙古 呼和浩特 010031; 2.宁夏大学农学院/宁夏回族自治区反刍动物分子细胞育种重点实验室,宁夏 银川 750021 |
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| 基金项目： | 内蒙古自治区自然科学基金项目（2021MS03068）; 内蒙古自治区科技计划项目（2021GG0025）; 银川市校企联合创新专项（2022XQ008） |
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| 摘 要： | 茶多酚（tea polyphenols,TP）是茶叶中的多酚类物质,属于稠环芳香烃,在抗氧化、抗肿瘤、抑菌、抗病毒、抗辐射、抗心血管疾病等方面均发挥生物学作用。介绍了茶多酚的组成成分和理化性质,综述了茶多酚发挥抗炎作用主要涉及的信号通路及其在奶牛乳腺上皮细胞（bovine mammary epithelial cells,BMEC）炎性反应中的作用研究进展,以期为探究茶多酚在预防和治疗奶牛乳房炎中的应用价值提供参考。
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| 关 键 词： | 茶多酚 乳房炎 脂多糖 TLR4 NF-κB p65通路 |
| 收稿时间： | 2022-11-26 |
Regulatory Mechanisms of Tea Polyphenols and Their Intervention Effects on Dairy Cow Mastitis |
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| Baohua,JI Si-tong,ZHANG Chun-hua,Biligebatu,MA Yan-fen.Regulatory Mechanisms of Tea Polyphenols and Their Intervention Effects on Dairy Cow Mastitis[J].Animal Husbandry and Feed Science,2023,44(1):60-63. |
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| Authors: | Baohua JI Si-tong ZHANG Chun-hua Biligebatu MA Yan-fen |
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| Institution: | 1. Institute of Animal Nutrition and Feed,Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences,Hohhot 010031,China; 2. School of Agriculture,Ningxia University/Key Laboratory of Ruminant Molecular and Cellular Breeding of Ningxia Hui Autonomous Region,Yinchuan 750021,China |
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| Abstract: | Tea polyphenols （TP） are phenolic compounds in tea and belong to polycyclic aromatic hydrocarbons. They play biological roles in antioxidation, anti-tumor, bacteriostasis, anti-virus, anti-radiation and anti-cardiovascular diseases. In this paper, the compositions and physicochemical properties of TP are introduced, and the research progress on the signal pathways involved in the anti-inflammatory effect of TP and their roles in the inflammatory response of bovine mammary epithelial cells (BMEC) are reviewed, in hoping to provide references for exploring the potential application value of TP in the prevention and treatment of dairy cow mastitis. |
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| Keywords: | tea polyphenols mastitis lipopolysaccharide TLR4 NF-κB p65 pathway |
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