| 阿留申病细小病毒的分离及VP2基因遗传衍生分析 |
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| 引用本文： | 华育平,马建.阿留申病细小病毒的分离及VP2基因遗传衍生分析[J].畜牧兽医学报,2005,36(9):960-963. |
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| 作者姓名： | 华育平 马建 |
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| 作者单位： | 东北林业大学野生动物资源学院,哈尔滨,150040 |
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| 基金项目： | 黑龙江省科技攻关项目（20020101416） |
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| 摘 要： | 水貂阿留申病（Aleutian disease of mink，AD）是水貂的一种慢性传染病，病原为阿留申病细小病毒（Aleutian mink disease parvovirus，AMDV），属细小病毒科、细小病毒属。AD自1940年发现以来至今60年里，已经普遍存在于世界各地人工养殖的水貂种群中。对水貂养殖业造成了不可估量的经济损失。
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| 关 键 词： | 水貂阿留申病病毒 VP2基因 遗传变异 |
| 文章编号： | 0366-6964（2005）09-0960-04 |
| 收稿时间： | 2004-12-02 |
| 修稿时间： | 2004-12-02 |
Isolation of Aleutian Mink Disease Parvovirus and Genetic Variation Analysis of VP2 Gene |
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| HUA Yu-ping,MA Jian.Isolation of Aleutian Mink Disease Parvovirus and Genetic Variation Analysis of VP2 Gene[J].Acta Veterinaria et Zootechnica Sinica,2005,36(9):960-963. |
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| Authors: | HUA Yu-ping MA Jian |
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| Abstract: | The samples of minks from several main mink farming areas were detected by the methods of counter immunoelectrophoresis(CIEP)and polymerase chain reaction (PCR)and some data about Aleutian mink disease parvovirus(ADV)infection in farmed mink was obtained. Partial VP2 genes,which include a hypervariable region, of 16 ADV strains isolated were separately amplified by PCR and sequenced. Comparison and analysis of these genes sequences and the related sequences of ADV-G,ADV-Utah1 and ADV-K that reported in the USA and European had been completed. The result shows that : firstly, the closed relationship exists between domestic ADV isolates and foreign ones,and the domestic AD maybe introduced from foreign countries. Secondly, the ADV isolates we obtained have a high genetic diversity. DL1, DL2, MS3 and MS5 may be some new types of ADV because of so obvious differences compared with foreign isolates in the genes sequences. |
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| Keywords: | ADV isolates VP2 gene genetic variation analysis |
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