Progress of urinary exosome microRNAs in kidney diseases |
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| Authors: | Lü Jie LI Min-min |
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| Institution: | Center of Clinical Laboratory Medicine, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China |
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| Abstract: | Exosomes are extracellular vesicles that are actively released from all types of cells to various body fluids under the physiological and pathological conditions. It can be used as an intercellular signaling carrier by transferring specific components such as proteins, lipids and nucleic acids, which mediates the transmission of information between cells, thereby affecting the biological function of the recipient cells. Urinary exosomes are secreted by various cells in the urinary system and released into the urine. Recent studies have shown that changes of urinary exosome microRNAs can be used as biomarkers in kidney diseases for monitoring the changes of diseases and judging prognosis, and also have important value in the disease treatment. This article reviews the progress of urinary exosome microRNAs in kidney diseases. |
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| Keywords: | Exosome Urine Kidney diseases MicroRNAs |
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