| 乳铁素参与乳房链球菌对乳腺上皮细胞的粘附 |
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| 引用本文： | 方维焕,张晓峰.乳铁素参与乳房链球菌对乳腺上皮细胞的粘附[J].中国兽医学报,2003,23(1):35-37. |
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| 作者姓名： | 方维焕 张晓峰 |
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| 作者单位： | 1. 浙江大学,动物预防医学研究所,浙江,杭州,310029
2. 美国田纳西大学 动物科学系,美国 |
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| 摘 要： | 免疫印迹试验表明，试验用的3株乳房链球菌（Streptococcus uberis)菌株均可与乳铁素（Lactoferrin)结合。培养基中加入乳铁素或乳清可以显著促进细菌与乳腺上皮细胞之间的粘附，抗乳铁素抗体可以特异性地抑制乳铁素或乳清预处理细菌与乳腺上皮细胞的粘附。乳铁素在细菌和细胞之间起着桥梁分子作用。有助于细菌与乳腺上皮细胞之间的粘附和乳腺感染的建立。
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| 关 键 词： | 乳铁素 乳房链球菌 乳腺上皮细胞的 粘附 奶牛 乳房炎 |
| 文章编号： | 1005-4545(2003)01-0035-03 |
| 修稿时间： | 2001年5月23日 |
Lactoferrin Involved in Adherence of Streptococcus uberis to Bovine Mammary Epithelial Cells |
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| Stephen P.Oliver.Lactoferrin Involved in Adherence of Streptococcus uberis to Bovine Mammary Epithelial Cells[J].Chinese Journal of Veterinary Science,2003,23(1):35-37. |
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| Authors: | Stephen POliver |
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| Abstract: | Three Streptococcus uberis isolates were fo und to be bound with purified lactoferrin and lactoferrin in milk.Addition of la ctoferrin or milk to the culture medium increased S.uberis adherence to the mammary epithelial cells.Increased adherence could be antagonized by rabbit anti -bovine lactoferrin antibody.These results suggest that lactoferrin may functio n as a bridging molecule between S.uberis and bovine mammary epithelial cell s,favoring the establishment of intramammary bacterial infection. |
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| Keywords: | Streptococcus uberis lactoferrin mammary e pithelial cells adherence |
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