| 辅酶Q10及其合成限速酶编码基因的研究进展 |
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| 引用本文： | 张新浩,董雅娟,牛召珊,赵仕全,杨莉,柏学进.辅酶Q10及其合成限速酶编码基因的研究进展[J].中国畜牧兽医,2014,41(12):220-224. |
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| 作者姓名： | 张新浩 董雅娟 牛召珊 赵仕全 杨莉 柏学进 |
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| 作者单位： | 1. 青岛农业大学动物胚胎中心, 山东青岛 266109;2. 山东省黑牛繁育工程技术研究中心, 山东青岛 266109;3. 山东布莱凯特黑牛科技股份有限公司, 山东淄博 256306 |
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| 基金项目： | 国家科技支撑计划(2012BAD39B00);肉牛精细化健康养殖模式构建与示范(2012BAD39B05-1);山东省牛产业体系创新团队(SDAIT-12-011-01). |
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| 摘 要： | 辅酶Q10(CoQ10)是一种醌环类化合物,广泛存在于动植物及微生物细胞内,其在氧化磷酸化、细胞凋亡、体内自由基清除和增强机体免疫力等方面起着重要作用,被生物学家称为维生素Q.CoQ10合成酶编码基因的多态性影响机体内CoQ10水平,这为将其作为候选基因用于布莱凯特黑牛育种提供了可能.作者就CoQ10参与氧化磷酸化和清除自由基的作用机制、合成限速酶编码基因定位及结构等内容进行阐述,为借助分子标记技术促进国内肉牛新品种培育提供参考.
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| 关 键 词： | CoQ10 布莱凯特黑牛 PDSS1 COQ2 分子标记 |
| 收稿时间： | 2014-04-17 |
Research Advance on CoQ10 and the Genes Encoding its Rate-limiting Enzyme |
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| ZHANG Xin-hao,DONG Ya-juan,NIU Zhao-shan,ZHAO Shi-quan,YANG Li,BAI Xue-jin.Research Advance on CoQ10 and the Genes Encoding its Rate-limiting Enzyme[J].China Animal Husbandry & Veterinary Medicine,2014,41(12):220-224. |
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| Authors: | ZHANG Xin-hao DONG Ya-juan NIU Zhao-shan ZHAO Shi-quan YANG Li BAI Xue-jin |
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| Institution: | 1. Animal Embryo Engineering Center, Qingdao Agricultural University, Qingdao 266109, China;2. Shandong Black Cattle Breeding Engineering Technological Research Center, Qingdao 266109, China;3. Shandong Black Cattle Science and Technology Co., Ltd., Zibo 256306, China |
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| Abstract: | CoQ10 is a quinone ring compound, existing in flora and fauna extensively, some biologists named it vitamin Q as it play a part in oxidative phosphorylation, regulation of apoptosis, radical scavenging, enhancing immunity and so on.The polymorphism of genes encoding CoQ10's synthase influence the level of CoQ10 and this makes it possible that treating the genes as markers in breeding of Black cattle.The mechanism of CoQ10 in oxidative phosphorylation and regulation of apoptosis, location and structure of the genes encoding CoQ10's synthase were summarized in this article.These materials provide reference for beef breeding in molecular marker technology. |
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| Keywords: | CoQ10 Black cattle PDSS1 COQ2 molecular marker |
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