| 养殖鲟鱼肝硬化病的器官和组织病理学观察 |
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| 引用本文： | 杨仕豪,潘连德,郑串.养殖鲟鱼肝硬化病的器官和组织病理学观察[J].大连海洋大学学报,2016(6):623-629. |
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| 作者姓名： | 杨仕豪 潘连德 郑串 |
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| 作者单位： | 上海海洋大学省部共建水产种质资源发掘与利用教育部重点实验室,上海,201306 |
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| 基金项目： | 水产动物遗传育种上海市协同创新中心项目(ZF1206) |
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| 摘 要： | 为了明确养殖鲟鱼Acipenser sinensis肝硬化的致病因素及诊治方法,在3批次现场采集病样(共计41尾)中,选取9尾具典型症状的患病鲟鱼,对其重要组织器官进行采样,制作石蜡切片,H-E染色,对自然发病的疑似肝硬化杂交鲟进行了病理解剖观察和组织病理学研究,并对其组织病理变化及发病机理进行了分析。结果表明:1、2、3、9号病样表现出明显肝组织病变,肝组织内出现弥漫性纤维增生等典型肝纤维化症状;脾充血,空泡变性、坏死;胃、肠充血,炎性细胞浸润,肠绒毛坏死甚至脱落;其他器官(鳃、心等)组织轻微淤血、炎症;结合各器官症状和组织病变及参考相关研究,确定本病例为鲟鱼肝病,具体诊断为鲟鱼肝硬化。研究表明,鲟鱼肝硬化的器官和组织病理学诊断特征为肝淤血和溃疡,肝腹水,肝血窦扩张、炎性细胞浸润、组织空泡化、组织纤维化。
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| 关 键 词： | 鲟鱼 肝硬化 组织病理 器官病理 |
Pathology of organ and tissue in farmed sturgeons with hepatocirrhosis |
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| Abstract: | The pathoanatomy and histopathology were investigated in 9 samples (41 individuals) of cultured hybrid sturgeon suffered from hepatocirrhosis collected from flowing water sturgeon farms in order to evaluate the pathological changes and pathogenesis of hepatocirrhosis in fanned Chinese sturgeon Acipenser sinensis.It was that there were obvious pathological changes in liver including fiber diffusion,hyperplasia,and atypical hepatic fibrosis in No.1,No.2,No.3,and No.9 samples.The splenic hyperemia,vacuolar degeneration,and necrosis,stomach and intesfinal hyperemia,inflammatory cell infiltration,and necrosis of the intestinal villi,even shedding,were also observed,with slight congestion and inflammation in other organs tissues (gill and heart).Based on the organ symptoms and tissue lesion,the case for sturgeon liver disease was considered as sturgeon hepatocirrhosis.The findings indicate that sturgeon hepatocirrhosis is characterized by liver congestion and ulcer,liver ascites,liver blood sinus dilation,inflammatory cell infiltration,tissue degeneration and tissue fibrosis. |
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| Keywords: | Acipenser sinensis hepatocirrhosis histopathology organ pathology |
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