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杀鲑气单胞菌对鲟的杂交致病性及病理变化分析
引用本文:张飘,杨霞,胡安东,潘吉脉,刘妍罕,曾茂芹,程振涛,姜海波,文明.杀鲑气单胞菌对鲟的杂交致病性及病理变化分析[J].中国动物传染病学报,2021(2):58-64.
作者姓名:张飘  杨霞  胡安东  潘吉脉  刘妍罕  曾茂芹  程振涛  姜海波  文明
作者单位:贵州大学动物科学学院;贵州大学动物疫病研究所;贵州省动物疫病与兽医公共卫生重点实验室
基金项目:贵州省科技支撑计划项目(黔科合支撑[2016]2502号、黔科合支撑[2016]2511号、黔科合支撑[2017]2532号);贵州省科技平台及人才团队计划项目(黔科合平台人才[2018]5253号);贵州省研究生教育创新计划项目(GZZ2017002)。
摘    要:为初探虹鳟鱼源杀鲑气单胞菌对杂交鲟是否具有感染性及人工感染后的主要临床症状及病理变化.本研究使用虹鳟鱼源杀鲑气单胞菌对杂交鲟进行人工感染,通过对半数致死量的测定、临床症状观察、发病杂交鲟解剖学变化观察及组织病理切片观察(HE染色)来确定杀鲑气单胞菌对杂交鲟是否具有致病性及致死性.结果 显示:虹鳟鱼源杀鲑气单胞菌对杂交鲟...

关 键 词:杂交鲟  杀鲑气单胞菌  病理变化

Analysis of Pathogenicity and Pathological Changes of Aeromonas Salmonicida on Hybrid Sturgeon
ZHANG Piao,YANG Xia,HU Andong,Pan Jimai,LIU Yanhan,ZENG Maoqin,CHENG Zhentao,JIANG Haibo,WEN Ming.Analysis of Pathogenicity and Pathological Changes of Aeromonas Salmonicida on Hybrid Sturgeon[J].Chinese Journal of Animal Infectious Diseases,2021(2):58-64.
Authors:ZHANG Piao  YANG Xia  HU Andong  Pan Jimai  LIU Yanhan  ZENG Maoqin  CHENG Zhentao  JIANG Haibo  WEN Ming
Institution:(College of Animal Science,Guizhou University,Gufyang 550025,China;Institute of Animal Diseases,Guizhou University,Guiyang 550025,China;Key Laboratory of Animal Disease and Veterinary Public Health of Guizhou Province,Guiyang 550025,China)
Abstract:To explore the infectivity of Aeromonas Salmonidae from rainbow trout to the hybrid sturgeon and the main clinical symptoms and pathological changes after artificial infection.The method of measuring median-lethal dose,observation of clinical symptoms,anatomical changes of hybrid sturgeon and observation of histopathological section(HE staining)were carried out.Whether it is pathogenic and lethal to hybrid sturgeon?It turns out it does,and the median lethal dose was 7.9×106 CFU/mL when injected into the gluteal fin;Increase of mucus secretion on the body surface of hybrid sturgeon;Multi-organ with bleeding points,serious cases have ulcer stove formation,pathological slicing observation found that after infection hybrid crucibles,muscles,fat,intestines and heart tissues have obvious pathological changes,of which the pathological changes are more obvious parts of the gill filament twisting and shedding,intestinal fluff shedding and liver cells of the blistering degeneration.In summary,It can be inferred that Aeromonas salmonicida can cause hybrid sturgeon disease and is lethal to hybrid sturgeon.Its main clinical symptoms are the same as furunculosis.
Keywords:Hybrid sturgeon  aeromonas salmonicida  pathological changes
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