| 木耳提取物和余渣的止咳化痰功效 |
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| 引用本文： | 孔祥辉,马银鹏,杨国力,张介驰,陈喜君,张丕奇,王辉,王笑庸,陈鹤.木耳提取物和余渣的止咳化痰功效[J].食用菌学报,2017(3):42-45. |
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| 作者姓名： | 孔祥辉 马银鹏 杨国力 张介驰 陈喜君 张丕奇 王辉 王笑庸 陈鹤 |
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| 作者单位： | 1. 黑龙江省科学院微生物研究所,黑龙江哈尔滨150010;黑龙江省科学院高技术研究院,黑龙江哈尔滨150020;2. 黑龙江省科学院微生物研究所,黑龙江哈尔滨,150010;3. 黑龙江众生生物工程有限公司,黑龙江哈尔滨,150028 |
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| 基金项目： | 黑龙江省科研机构创新能力提升专项(YC2015D002)，哈尔滨市应用技术研究与开发资金(科技项目)项目(2016RAXYJ046)，黑龙江省科学院基金项目(KY16BKXH10) |
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| 摘 要： | 采用水提法获得木耳(Auricularia auricula)提取物和余渣,并借助中药清肺润肺小鼠模型研究它们的止咳化痰功效。结果表明:提取物和余渣得率分别为12.3%和71.6%;3 min内提取物高剂量组(200mg/kg·d)咳嗽次数为(7.67±3.28),余渣高剂量组咳嗽次数为(7.75±3.28),两者与空白对照组咳嗽次数(21.25±3.37)之间均存在极显著性差异(P0.01),说明提取物和余渣都有显著的止咳作用;虽然提取物和余渣的小鼠酚红排泌量增加幅度均高于阳性对照组,但仅余渣高剂量组与阳性对照组之间存在显著性差异(P0.05),说明余渣化痰效果优于提取物。
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| 关 键 词： | 木耳 活性 清肺润肺 |
Improved Control of Moist Cough Symptoms with Auricularia auricular Water Extract and Extraction Residue |
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| KONG Xianghui,MA Yinpeng,YANG Guoli,ZHANG Jiechi,CHEN Xijun,ZHANG Piqi,WANG Hui,WANG Xiaoyong,CHEN He.Improved Control of Moist Cough Symptoms with Auricularia auricular Water Extract and Extraction Residue[J].Acta Edulis Fungi,2017(3):42-45. |
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| Authors: | KONG Xianghui MA Yinpeng YANG Guoli ZHANG Jiechi CHEN Xijun ZHANG Piqi WANG Hui WANG Xiaoyong CHEN He |
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| Abstract: | Aqueous extract and the residue of Auricularia auricula fruit bodies from water extraction were evaluated for their effects on treating moist cough using the ammonia-induced mice cough model.The recover rate of aqueous extract and residue were 12.3％ and 71.6％,respectively.Cough frequency in high dose group (200 mg/kg) of extract and residue were 7.67-± 3.28 and 7.75 ± 3.28 respectively,which were significantly less than the cough frequency of the control (P＜0.01),suggesting that both aqueous extract and residue had significant cough-relieving effect.Compared to the positive control group,phenol red secretion from mice were increased in aqueous extract and residue treatment groups.However,only the high residue dosage group showed a statistically significant difference compared to the positive control (P＜0.05),suggesting the residue had a superior effect on treating moist cough than the aqueous extract. |
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| Keywords: | Auricularia auricular biological activity lung clearing and moisturizing effect |
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