| 四川红桔皮化学成分对家兔耳(足)螨病治疗试验 |
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| 引用本文： | 刘俊华,王芳生,董文其.四川红桔皮化学成分对家兔耳(足)螨病治疗试验[J].中国兽医学报,1990(2). |
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| 作者姓名： | 刘俊华 王芳生 董文其 |
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| 作者单位： | 兽医大学军事兽医研究所
(刘俊华，王芳生)，兽医大学军事兽医研究所(董文其) |
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| 摘 要： | 用从四川红桔皮中提取的7种化学成分,即川陈皮素(nobiletin)、蜜桔素(tangeratin),5-去甲川陈皮素(5-o-demethyl nobiletin)、4',5,7,8-四甲氧基黄酮(4',5,7,8-tetrahydroxylflavone)、麝香草酚(thymol)、β-谷甾醇(β-sitosterol)、异橙黄酮(isosi-nensetin) (依次用A,B,C,D,E,F,G代表),对兔螨进行了离体杀灭比较试验。结果以C、D、G杀螨力较强,其中又以G最强,1000倍稀释G液15 min能杀死10/10螨虫,C、D液则需4 h才能杀死10/10螨虫,对照组14 h仍有7/10螨虫存活。用G和桔皮油、辛硫磷对比杀螨,G 5～20 min、枯皮油5～30 min均可杀死10/10螨虫,而辛硫磷在6 h还有3/10活螨.以不同稀释倍数G液对5只耳螨兔进行治疗试验,结果250-500倍稀释G液治疗3 d 5/5治愈,1 000-10 000倍稀释者需7～14 d才全部治愈.进而用250-500倍稀释G液对不同养兔单位的208只耳(足)螨兔扩大治疗试验,有效率为100％,其中连续用药2～3次者,97.3％完全治愈,2.7％好转;仅治疗1次者,92％完全治愈,8％好转.用G液治疗兔螨病,无任何毒副作用.
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| 关 键 词： | 桔皮 化学成分 治疗 兔螨病 |
Treatment for Ear ( Foot ) Scabies of Rabbit with Same Components of Citrus Reticulata Blano |
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| Liu Junhua et al.Treatment for Ear ( Foot ) Scabies of Rabbit with Same Components of Citrus Reticulata Blano[J].Chinese Journal of Veterinary Science,1990(2). |
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| Authors: | Liu Junhua |
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| Abstract: | The mitecidal effect of orange peel oil land the chemical constituents of the orange peel have been reported previously. In this experiment, 7 components ate selected for evaluating their mitecidal potency in vitro individually. It was shown that 5 -0-demethyl nobiletin occupies first place, phoxin comes second. And then, two hundred and eight cases of rabbit acabies are treated with 5 - 0 -demethyl nobiletin diluted 250-500 times. Its effective rate was 100%. If administer for 2 - 3 times,97.3% of infested rabbits could be cured; even though only once, the curative rate may be up to 92%. No toxic and side effects are found. |
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| Keywords: | Citrus reticulata Blano chemical component treatment rabbit scabies |
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