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| 牦牛胎盘粉对亚急性衰老小鼠部分组织中NO含量的影响 | |
| 引用本文： | 高丽英,尚海忠,张寿,宁鹏,常兰,陈长江.牦牛胎盘粉对亚急性衰老小鼠部分组织中NO含量的影响[J].安徽农业科学,2009,37(18):8523-8524. |
| 作者姓名： | 高丽英 尚海忠 张寿 宁鹏 常兰 陈长江 |
| 作者单位： | 1. 青海省海西州动物疫预防病控制中心,青海海西州,817000 2. 青海省海西州兽医卫生监督所,青海海西州,817000 3. 青海大学农牧学院,青海西宁,810003 |
| 摘 要： | 目的]研究牦牛胎盘粉对亚急性衰老小鼠心、肝、脾、肺、肾、骨骼肌中一氧化氮（NO）含量的影响。方法]将健康小鼠随机分为正常对照组、模型纽、阳性对照组、低海拔胎盘组、中海拔胎盘组和高海拔胎盘组，将除正常对照组外的其他5组用D-半乳糖，造亚急性衰老小鼠模型；然后对低、中和高海拔胎盘组的小鼠建模11d后，每天灌胃牦牛胎盘粉，剂量为40mg／kg。阳性对照组每天灌服维生素E 100mg／kg，45d后观察心、肝、脾、肺、肾组织中一氧化氮（NO）含量。结果]高原牦牛胎盘粉可明显降低小鼠心、肝、脾、肺、肾组织中一氧化氮（NO）含量（P〈0.01）。结论]高原牦牛胎盘粉有很好的抗衰老作用。 |
| 关 键 词： | 牦牛胎盘 小鼠 抗衰老 NO |
The Effect of Yak Placenta Powder on NO Content in Some Organs of Subacute Aging Model Mice |
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| Institution: | GAO li-ying et al ( Center of Animal Disease Control and Prevention, Haixi, Qinghai 817000) |
| Abstract: | Objective] The purpose was to study the effect of yak placenta powder on NO content in heart,liver,spleen,lung and kidney,skeleton muscle of subacute aging model mice.Method]The healthy mice were randomly divided into normal control group,model group,positive control group,low-elevation placenta group,middle-elevation placenta group and high-elevation placenta group.Five groups except for normal control group were used to construct subacute aging mice model by D-galactose.11 days later,the mice of the low-elevation,middle-elevation and high-elevation yak placenta powder groups were gastricly lavaged with yak placenta powder with its dose being of 400 mg/kg,respectively,positive control group were gastricly lavaged with Vitamin E100 mg/kg.After 45 days,the content of NO in heart,liver,spleen,lung and kidney,skeleton muscle were determinated.Result] The results showed that yak placenta powder obviously decrease the content of NO in heart,liver,spleen,lung and kidney,skeleton muscle,indicating that the yak placenta powder has good anti-aging effect. |
| Keywords: | NO |
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