Cardiorespiratory and anesthetic effects produced by the combination of
butorphanol,medetomidine and alfaxalone administered intramuscularly in Beagle
dogs |
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| Authors: | Jongsung LEE Sangil SUH Ran CHOI Changbaig HYUN |
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| Institution: | 1)Section of Small Animal Internal Medicine, College of Veterinary Medicine, Kangwon National University, Chuncheon, Korea |
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| Abstract: | This study evaluated anesthesia quality, degree of analgesia and cardiorespiratory
parameters after intramuscular (IM) injection of a combination of butorphanol (0.1 mg/kg),
medetomidine (10 µg/kg) and alfaxalone (1.5 mg/kg) in ten healthy adult
Beagle dogs. Rectal temperature (T), heart rate (HR), respiratory rate
(fR), arterial pressure, arterial blood gases and M-mode
echocardiographic left ventricular (LV) indices were measured before drug administration
and every 10 min thereafter until extubation. Mean duration of anesthesia, recovery and
analgesia were 89 ± 17, 6 ± 1 and 80 ± 12 min. HR, fR, partial
pressure of arterial CO2 and O2, arterial pressure, and LV
contractility were significantly altered during anesthesia. IM administration of the drug
combination provided acceptable anesthesia, but produced substantial cardiorespiratory
suppression. |
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| Keywords: | alfaxalone anesthesia butorphanol canine medetomidine |
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