Sequence and phylogenetic analysis of neuraminidase genes of H9N2 avian influenza viruses isolated from commercial broiler chicken in Iran (2008 and 2009) |
| |
| Authors: | Masoud Soltanialvar Hamid Shoushtari Mohamadhasan Bozorgmehrifard Saeed Charkhkar Farshad Akbarnejad |
| |
| Institution: | (1) Science and Research Branch, Islamic Azad University (IAU), Tehran, Iran;(2) Division of Avian Diseases and Research, Razi Vaccine and Serum Research Institute, Karaj, Tehran, Iran;(3) Division of Avian Diseases, Tehran University, Tehran, Iran;(4) Division of Avian Diseases, Science and Research Branch, Islamic Azad University, Tehran, Iran;(5) Division of Avian Diseases, Islamic Azad University, Shoushtar Branch, Khuzestan, Iran |
| |
| Abstract: | A total of 512 tissue samples collected from 30 farms located in various states of Iran during 2008–2009 as part of a program
to monitor avian influenza viruses (AIVs) infection in Iran’s poultry population. To determine the genetic relationship of
Iranian viruses, neuraminidase (NA) genes from ten isolates of H9N2 viruses isolated from commercial chickens in Iran during
2008–2009 were amplified and sequenced. The viruses’ neuraminidase gene was >90% similar to those of A/Quail/Hong Kong/G1/97
(H9N2) sublineage. The neuraminidase stalk regions in these Viruses had no deletion as compared to that of chicken/Beijing/1/94
sublineage (Beijing-like viruses) and the two human isolates A/HK/1073/99, A/HK/1074/99. Phylogenetic analysis of neuraminidase
(NA) gene showed that it shares a common ancestor A/Quail/Hong Kong/G1/97 isolate which had contributed the internal genes
of the H5N1 virus. The results of this study indicated that No (Beijing-like) virus and (Korean-like) virus were found in
chickens in Iran, and the NA genes of H9N2 influenza viruses circulating in Iran during the past years were well conserved
and the earlier Iranian isolates may be considered to represent such a progenitor. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
