Copper storage disease with intravascular haemolysis in a Bedlington terrier |
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| Authors: | A D J WATSON D J MIDDLETON J E ILKIW |
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| Institution: | Departments of Veterinary Clinical Studies and Veterinary Pathology, The University of Sydney, New South Wales 2006 |
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| Abstract: | A 5-year-old male Bedlington terrier was found to have haemoglobinuria from intravascular haemolysis. The owners reported also recent vomiting, occasional diarrhoea, reduced activity and increased drinking and urination. A diagnosis of inherited copper storage disease, as previously described in this breed, was established by demonstrating characteristic light and electron microscopic changes and copper content of 7, 717 micrograms/g in biopsied liver. Treatment by chelation with d-penicillamine and a low copper diet was instituted and the dog remains well 10 months later. Intravascular haemolysis is rare in dogs and an uncommon finding in Bedlington terriers with copper storage disease. |
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