| 大花君子兰总生物碱抗肿瘤作用的研究 |
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| 引用本文： | 于妮娜,包海鹰,何忠梅.大花君子兰总生物碱抗肿瘤作用的研究[J].吉林农业大学学报,2011,33(4):399-402,407. |
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| 作者姓名： | 于妮娜 包海鹰 何忠梅 |
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| 作者单位： | 吉林农业大学中药材学院,长春,130118 |
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| 基金项目： | 长春市惠宝君子兰科技养殖及药理活性研究项目 |
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| 摘 要： | 采用MTT法观察大花君子兰总生物碱(简写为TACMR)对体外培养的人肺癌细胞NCI-H446、人胃癌细胞SGC-7901、人乳腺癌细胞MCF-7和人肝癌细胞SMMC-7721 4种细胞株的增殖抑制作用；用小鼠移植性肿瘤法检测TACMR对小鼠H22肝癌的生长抑制作用，并通过脾指数和胸腺指数等指标综合考察TACMR对肿瘤小...
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| 关 键 词： | 大花君子兰 总生物碱 MTT法 H22荷瘤小鼠 |
Anti-Tumor Effect of Total Alkaloids from Clivia miniata |
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| YU Ni-na,BAO Hai-ying,HE Zhong-mei.Anti-Tumor Effect of Total Alkaloids from Clivia miniata[J].Journal of Jilin Agricultural University,2011,33(4):399-402,407. |
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| Authors: | YU Ni-na BAO Hai-ying HE Zhong-mei |
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| Institution: | YU Ni-na,BAO Hai-ying,HE Zhong-meiCollege of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China |
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| Abstract: | In vitro,the inhibitory effects of total alkaloids from Clivia miniata Regel(TACMR) on proliferation of NCI-H446,SGC-7901,MCF-7,and SMMC-7721 were measured by MTT colorimetric assay.The inhibitory effects of TACMR on H22hepatic cancer was observed in mice with subcutaneous inoculation on the tumor cells and its effect on immunological function of mice bearing tumor by observing the influence to spleen index,thymus index and so on.In vitro,the results of MTT showed that TACMR inhibited proliferation of NCI-H... |
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| Keywords: | Clivia miniata Regel total alkaloids MTT H22tumor bearing mice |
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