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牛病毒性腹泻病毒与宿主细胞的相互作用研究
引用本文:韩猛立,黄新,宋天增,杨井泉,薄新文,钟发刚.牛病毒性腹泻病毒与宿主细胞的相互作用研究[J].湖北农业科学,2012,51(8):1519-1523.
作者姓名:韩猛立  黄新  宋天增  杨井泉  薄新文  钟发刚
作者单位:1. 新疆农垦科学院/新疆生产建设兵团绵羊繁育生物技术重点实验室,新疆石河子,832000
2. 西藏自治区农牧科学院畜牧兽医研究所,拉萨,626000
3. 新疆农垦科学院/新疆生产建设兵团绵羊繁育生物技术重点实验室,新疆石河子832000;石河子大学动物科技学院,新疆石河子832003
基金项目:“973计划”前期研究专项,国家自然科学基金,新疆农垦科学院青年科学基金
摘    要:自1946年Olafson等首次在美国纽约州发现牛病毒性腹泻病毒(BVDV)以来,该病毒在世界各地广泛流行和传播,尤其对一些畜牧业发达国家的奶业和牛肉业造成了巨大损失.了解牛病毒性腹泻病的致病机理,研制出更加安全可靠有效的疫苗,对控制该病的发生和蔓延尤为重要.对BVDV的病原学、生物学特性以及对宿主细胞的相互作用等进行了阐述,以期为BVDV的预防及治疗奠定基础.

关 键 词:牛病毒性腹泻病毒(BVDV)  分子生物学  细胞生物学  宿主细胞

Research Progress of Interaction Between Bovine Viral Diarrhea Virus and Host Cell
HAN Meng-li , HUANG Xin , SONG Tian-zeng , YANG Jing-quan , BO Xin-wen , ZHONG Fa-gang.Research Progress of Interaction Between Bovine Viral Diarrhea Virus and Host Cell[J].Hubei Agricultural Sciences,2012,51(8):1519-1523.
Authors:HAN Meng-li  HUANG Xin  SONG Tian-zeng  YANG Jing-quan  BO Xin-wen  ZHONG Fa-gang
Institution:1(1.Xinjiang Academy of Agricultural and Reclamation Sciences/Key Laboratory of Sheep Breeding and Development Technology of Xinjiang Production & Construction Corps,Shihezi 832000,Xinjiang,China;2.Institute of Animal Science,Tibet Autonomous Prefecture Academy of Agricultural and Animal Husbandry Science,Lhasa 626000,Tibet,China;3.College of Animal Science and Technology,Shihezi University Shihezi 832003,Xinjiang,China)
Abstract:The bovine viral diarrhea virus(BVDV) has been prevalenced and disseminated worldwidely,since it was confirmed by Olafson in New York State in 1946.This virus caused large losses in dairy and beef industries,especially in the countries with advanced animal husbandry.Understanding the pathogenic mechanism and utilization of the safe and effective vaccine are very important for the control of occurrence and spread of this disease.The etiology,biological characteristics and interaction of host cell BVDV were described so as to provide the basic data for the prevention and therapy of BVDV.
Keywords:bovine viral diarrhea virus  molecular biology  cell biology  host cell
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