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| 贵州南五味子多糖对鸡细胞免疫和体液免疫的影响 | |
| 引用本文： | 王宏军,蒋红,邓旭明.贵州南五味子多糖对鸡细胞免疫和体液免疫的影响[J].中国兽医学报,2011,31(6). |
| 作者姓名： | 王宏军 蒋红 邓旭明 |
| 作者单位： | 1. 吉林大学,畜牧兽医学院,吉林长春130062;辽宁医学院,辽宁锦州121001 2. 辽宁医学院,辽宁锦州,121001 3. 吉林大学,畜牧兽医学院,吉林长春130062 |
| 基金项目： | 国家科技支撑计划资助项目(2008BADB4B04-4); 辽宁省教育厅资助项目(L2010256) |
| 摘 要： | 选用600只15日龄海兰褐雏鸡,随机分为5个处理,每个处理3个重复,每个重复40只鸡,皮下注射贵州南五味子多糖10、20mg/kg、黄芪多糖20mg/kg、环磷酰胺40mg/kg及生理盐水。空白对照组,连续给药3d后免疫新城疫疫苗,分别于免疫后7、14、21、28和35d时,各处理组随机抽取8只鸡检测各项免疫指标,探讨不同处理组对雏鸡免疫功能的影响。本试验结果表明,皮下注射10～20mg/kg贵州南五味子多糖可显著促进鸡外周血T淋巴细胞增殖,IL-2的产生(P<0.01);可使CD4+/CD8+淋巴细胞比值明显升高(P<0.01);可使鸡体内抗ND抗体滴度明显升高(P<0.01);可使法氏囊、胸腺的脏器指数均明显升高(P<0.01)。 |
| 关 键 词： | 南五味子 多糖 鸡 细胞免疫 体液免疫 |
Effects of Guizhou Kadsura polysaccharide(GKP) on cellular and humoral immunity of chicken |
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| WANG Hong-jun,JIANG Hong,DENG Xu-ming.Effects of Guizhou Kadsura polysaccharide(GKP) on cellular and humoral immunity of chicken[J].Chinese Journal of Veterinary Science,2011,31(6). | |
| Authors: | WANG Hong-jun JIANG Hong DENG Xu-ming |
| Institution: | WANG Hong-jun1,2,JIANG Hong2,DENG Xu-ming1(1.College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China,2.Liaoning Medical University,Jinzhou,Liaoning 121001,China) |
| Abstract: | The experiment was conducted to investigate the effects of Guizhou Kadsura polysaccharide(GKP) on cellular and humoral immunity of in chickens by subcutaneous injection.A total of 600 Hy-line brown chickens aged 15-day-old were randomly divided into five groups with three replicates of forty chickens each.Experimental chinckens were injected with GKP(20 mg/kg and 10 mg/kg),APS(20 mg/kg),cyclophosphamide(40 mg/kg) respectively per day for and normal sodium(0.09%NaCl) respectively per day for three days.Then ... |
| Keywords: | Kadsura Japonica L polysaccharides chick cellular immunity humoral Immunity |
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