Research Progress on the Development of Mammary Glands |
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| Authors: | AN Pei-pei GUO Qian-qian LI Chun-yi |
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| Institution: | State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Animal and Plant Sciences of CAAS, Changchun 130112, China |
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| Abstract: | Mammary gland is a kind of exocrine glands and a dynamic organ.Structure of mammary gland changes throughout the female reproductive cycles.Development of mammary gland occurs in the defined stages that are closely linted to sexual development and reproduction, namely embryonic, prepubertal and pubertal stages, pregnancy, lactation and involution.In this review, the roles of epithelial-stromal (mesenchymal) interactions in embryonic and postnatal mammary development were summarized, elaborated the regulations of different kinds of hormones on the mammary development after pubertal stage, and described the discovery of mammary stem cell populations (MaSC) and selection markers of mice and human.The objective of this work was to learn the basic processes and potential regulation mechanisms of the mammary development to provide some help for the researchers in the field of mammary gland. |
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| Keywords: | mammary glands epithelial-stromal (mesenchymal) mammary stem cell |
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