| EDS_（76）灭活油乳剂疫苗的乳化工艺研究 |
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| 引用本文： | 吴祖立,马式虹,谈建明.EDS_（76）灭活油乳剂疫苗的乳化工艺研究[J].上海交通大学学报(农业科学版),1994(4). |
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| 作者姓名： | 吴祖立 马式虹 谈建明 |
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| 作者单位： | 上海农学院动物科学系 |
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| 摘 要： | 本研究是在研制成ＥＤＳ７６油乳灭活苗的基础上．用高压匀浆机代替原先使用的高速均装机来大批量生产疫苗．系统地研究了整个工艺流程中质量控制的各种因素，确定了水相和油相比例、乳化剂和稳定剂的ＨＬＢ值和乳化压力这３个技术参数．结果表明３３％的水相、复合乳化剂的ＨＬＢ值为７．１和在２０Ｐ压力下初次乳化。再在３０Ｐ压力下匀乳的工艺流程能获得稳定性好、粘度低、质量可靠的ＥＤＳ７６油乳剂灭活疫苗，适宜于生产实际使用．
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| 关 键 词： | EDS＿（76） 水相比例 HLB值 乳化压力 |
A STUDY ON TECHNOLOGY PROCESS IN MASSPRODUCING THE OIL-EMULSION VACCINE FOR EDS-76 |
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| Wu Zuli,Ma Shihong,Tan Jianming.A STUDY ON TECHNOLOGY PROCESS IN MASSPRODUCING THE OIL-EMULSION VACCINE FOR EDS-76[J].Journal of Shanghai Jiaotong University (Agricultural Science),1994(4). |
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| Authors: | Wu Zuli Ma Shihong Tan Jianming |
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| Abstract: | on the successful preparing EDS-76 oil-emulsion vaccine in the laboratory,the high-Pres sure homogenizer replaced the high-speed mixer to use for mass-producing the vaccine in this study.In order to control the-vaccine quality,the technology proccss had been studied through determing three parameters: the water-phase preportion the HLB value of compound emulsifier and the emulsifier and the emulsification pressures.The results showed that produced vaccine with 33 percent of water-phase proportion,7.1 HLB value of the compound emusifier, and the first emulsification under 20 P,again emulsification under 30 P,has good Stability and low viscosity,and is applicable to poultry industry. |
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| Keywords: | EDS-76 watr-proportion HLB value Emulsification pressure |
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