Porcine salmonellosis. II. Production of the generalized Shwartzman reaction by intravenous injections of disintegrated cells of salmonella cholerae-suis |
| |
| Authors: | Knut Nordstoga Morten Fjlstad |
| |
| Institution: | National Veterinary Institute and the Department of Microbiology and Immunology, Veterinary College of Norway, Oslo, Norway |
| |
| Abstract: | Three pigs were given intravenous injections of disintegrated cells of Salmonella cholerae-suis. One of these pigs developed macroscopic bilateral renal cortical necrosis. Histologic examination revealed, besides total cortical parenchymal necrosis, also severe vascular injury, characterized with fibrinoid necrosis of the vessel walls and fibrin thrombi within their lumina. These findings were interpreted as a result of a generalized Shwartzman reaction, provoked by the action of bacterial endotoxin. |
| |
| Keywords: | |
|
|
