| 谷胱甘肽过氧化物酶和谷胱甘肽转硫酶研究进展 |
| |
| 引用本文： | 马森.谷胱甘肽过氧化物酶和谷胱甘肽转硫酶研究进展[J].动物医学进展,2008,29(10). |
| |
| 作者姓名： | 马森 |
| |
| 作者单位： | 武夷学院化学系福建省高校绿色化工技术重点实验室,福建,武夷,354300 |
| |
| 摘 要： | 谷胱甘肽过氧化物酶（GSH—Px）和谷胱甘肽转硫酶（GST）是一对抗氧化酶。GSH—Px为含硒半胱氨酸，至少有4种同工酶，催化还原H2O2和有机氢过氧化物。GST不合硒，有多种同工酶，不能分解H2O2，但具有清除过氧化物和解毒的双重功能。二者广泛存在于组织细胞、红细胞、血浆和乳中，与细胞损伤、缺氧、中毒、衰老、多种疾病的发生有关；GSH—Px活性也与机体硒水平密切相关。文章综述了GSH—Px和GST的分类与结构、性质、作用、检测原理、动物临床方面的应用及研究进展。
|
| 关 键 词： | 谷胱甘肽过氧化物酶 谷胱甘肽转硫酶 研究进展 |
Progress on GSH-Px and GST |
| |
| MA Sen.Progress on GSH-Px and GST[J].Progress In Veterinary Medicine,2008,29(10). |
| |
| Authors: | MA Sen |
| |
| Institution: | Chemistry Department of Wuyi University;Fujian University Key Laboratory for Green Chemical Engineering Technology;Wuyi;Fujian;354300;China |
| |
| Abstract: | The GSH-Px and GST is a pair of antioxygented enzymes.GSH-Px,is a Cys containing Se,and it has 4 isoenzymes at least.It catalyzes and reduces H2O2 and origannic H-peroxide.GST does not contain Se,but it has many isoenzymes and could not decompose the H2O2.However it has two functions:eliminating peroxide and detoxification.GSH-Px and GST exist greatly in histocytes,erythrocytes,plasma,milk,and closely relate with the damage of cells,anoxia,poisoning,ageing and many diseases.The activity of GSH-Px is closely... |
| |
| Keywords: | glutathione peroxidase glutathione-S-transferase progress |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
