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超声提取甜菜多糖对小鼠免疫功能影响的研究
引用本文:常永志,包晓玮,杨晓君,何江梅,艾热提.超声提取甜菜多糖对小鼠免疫功能影响的研究[J].新疆农业科学,2011,48(7):1329-1332.
作者姓名:常永志  包晓玮  杨晓君  何江梅  艾热提
作者单位:新疆农业大学食品科学与药学学院,乌鲁木齐,830052
基金项目:新疆农业大学校前期项目
摘    要:目的]研究甜菜多糖对正常小鼠免疫功能调节作用的影响.方法]利用超声提取法得到80;的乙醇粗提物,通过紫外光谱测定甜菜提取物多糖含量为85.82;.将甜菜多糖配成(50 mg/(kg·d)),实验小鼠经胃灌注甜菜多糖,连续7d后处死,测定给药后小鼠脾脏及胸腺系数和腹腔巨噬细胞的吞噬功能.结果]甜菜多糖能提高小鼠免疫器官重量、巨噬细胞的吞噬功能.结论]甜菜多糖具有免疫调节活性作用.

关 键 词:超声波  甜菜多糖  免疫调节活性
收稿时间:2011-07-25

Preliminary Study on Effects of Beetroot Polysaccharide Extracted by Ultrasonic Wave on Immune Function of Mice
CHANG Yong-zhi,BAO Xiao-wei,YANG Xiao-jun,HE Jiang-mei,Aireti.Preliminary Study on Effects of Beetroot Polysaccharide Extracted by Ultrasonic Wave on Immune Function of Mice[J].Xinjiang Agricultural Sciences,2011,48(7):1329-1332.
Authors:CHANG Yong-zhi  BAO Xiao-wei  YANG Xiao-jun  HE Jiang-mei  Aireti
Institution:CHANG Yong-zhi,BAO Xiao-wei,YANG Xiao-jun,HE Jiang-mei,Aireti(College of Pharmacy,Xinjiang Agricultural University,Urumqi 830052,China)
Abstract:【Objective】 The purpose of this study was to investigate the effects of Beetroot polysaccharide on immune function of mice.【Method】 80% alcohol crude extract was obtained by ultrasonic wave and the determination of content of the beetroot polysaccharide via ultraviolet spectrophotometry was 85.82%.The experimental mice were infused via stomach with beetroot polysaccharide prepared for 50mg/kg·d,one time a day,and the experiment lasted 7 days.The mouse vivo immune function tests are carried out on the 8th day through the determination of their indices of thymus and spleen and the phagocytic activity of abdomen macraphages of mice.【Result】 Beetroot polysaccharide can increase the weight of the immune organs and phagocytotic function of the macrophages.【Conclusion】 Beetroot polysaccharide can regulate the immune functions of mice.
Keywords:ultrasonic wave  Beetroot Polysaccharide  activity of immune functions  
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