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自拟加味酸枣仁汤治疗肝血亏虚型失眠的疗效观察
作者姓名:张力  张守字
作者单位:北京老年医院, 北京 100095,北京老年医院, 北京 100095
基金项目:首都医学发展科研基金(2015-2043)
摘    要:目的 研究自拟加味酸枣仁汤对失眠肝血亏虚证患者的疗效以及对匹兹堡睡眠质量指数(pittsburgh sleep quality index,PSQI)和失眠严重程度指数(insomnia severity index,ISI)评分的影响。方法 将54例予常规治疗的肝血亏虚型失眠患者设为对照组,56例给予自拟加味酸枣仁汤治疗的失眠肝血亏虚证患者设为观察组,比较两组的PSQI、ISI、肝血亏虚证中医证候积分及临床疗效。结果 治疗后,两组PSQI、ISI、中医证候积分较治疗前均显著降低,且观察组显著低于对照组(P<0.05或P<0.01)。观察组临床总有效率91.07%,明显高于对照组77.78%,差异具有统计学意义(P<0.05)。结论 失眠肝血亏虚证患者采取自拟加味酸枣仁汤进行治疗,可显著改善睡眠质量,缓解失眠状态,从而提高临床疗效,促进患者早日康复。

关 键 词:失眠  自拟加味酸枣仁汤  肝血亏虚证  临床疗效
收稿时间:2018/5/23 0:00:00

Curative Effects Observation on Self-made Jiawei Suanzaoren Decoction in Treating Insomnia Patients with Liver-Blood Deficiency Syndrome
Authors:ZHANG Li and ZHANG Shouzi
Institution:Beijing Geriatric Hospital, Beijing 100095, China and Beijing Geriatric Hospital, Beijing 100095, China
Abstract:Objective To investigate the curative efficacy of self-made Jiawei Suanzaoren Decoction on insomnia patients with liver-blood deficiency syndrome and its effects on Pittsburgh sleep quality index (PSQI) and insomnia severity index (ISI) score. Methods A total of 54 insomnia patients with liver-blood deficiency syndrome receiving the routine treatment were included into the control group and another 56 cases receiving self-made Jiawei Suanzaoren Decoction were included into the observation group. The PSQI, ISI, TCM syndrome score of liver-blood deficiency syndrome and clinical efficacy were compared between the two groups. Results After treatment, the PSQI, ISI and TCM syndrome score of the two groups were significantly decreased than before treatment, and the observation group was significantly lower than the control group (P<0.05 or P<0.01). The total effective rate of the observation group was 91.07%, which was significantly higher than 77.78% of the control group. The difference was statistically significant. Conclusion The self-made Jiawei Suanzaoren Decoction is an effective way to ameliorate the sleep quality and alleviate insomnia on insomnia patients with liver-blood deficiency syndrome, which can improve the clinical efficacy and early recovery.
Keywords:insomnia  self-made Jiawei Suanzaoren Decoction  liver-blood deficiency syndrome  clinical efficacy
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