| 参芪清毒汤对维持性血液透析患者残余肾功能、营养指标及中医证候的影响 |
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| 作者姓名： | 刘杰 苏宝印 刘春茹 |
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| 作者单位： | 河北以岭医院, 河北 石家庄 050091,河北以岭医院, 河北 石家庄 050091,河北以岭医院, 河北 石家庄 050091 |
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| 基金项目： | 河北省中医药管理局基金项目（2010114）。 |
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| 摘 要： | 目的 观察在维持性血液透析（maintenance hemodialysis， MHD）的基础上加用参芪清毒汤对保护残余肾功能（residual renal function， RRF）、改善营养状况及中医证候的临床疗效。方法 选取2017年1月至2018年12月在河北以岭医院收治并行血液透析的慢性肾功能衰竭患者120例，随机分为观察组和对照组，各60例。对照组给予常规MHD和基础药物治疗，观察组在对照组的基础上加用参芪清毒汤，比较治疗前后两组患者的RRF、日均尿量、营养状况及中医证候积分。结果 治疗后，两组患者的中医证候各项积分均较治疗前有所下降（P<0.05），且观察组低于对照组（P<0.05）；治疗后，两组患者的RRF及日均尿量均较治疗前有所下降（P<0.05），观察组RRF及日均尿量均较对照组高（P<0.05）；治疗后，两组患者的MAC、MAMC、TSF、BMI均较治疗前升高（P<0.05），且观察组较对照组更高（P<0.05）；治疗后，两组患者的营养状况均较治疗前有明显改善（P<0.05），其中观察组营养良好者明显较对照组多，重度营养不良者明显较对照组少（P<0.05）。结论 在MHD和基础治疗之上加用参芪清毒汤，可以保护患者的RRF，改善营养状况和中医证候，疗效确切，值得临床进一步推广。
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| 关 键 词： | 维持性血液透析 参芪清毒汤 残余肾功能 中医证候 日均尿量 营养状况 |
| 收稿时间： | 2019/4/20 0:00:00 |
Effects of Shenqi Qingdu Decoction on Residual Renal Function, Nutritional Indicators and Traditional Chinese Medicine Syndromes of Maintenance Hemodialysis Patients |
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| Authors: | LIU Jie SU Baoyin and LIU Chunru |
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| Institution: | Hebei Yiling Hospital, Shijiangzhuang, Hebei 050091, China,Hebei Yiling Hospital, Shijiangzhuang, Hebei 050091, China and Hebei Yiling Hospital, Shijiangzhuang, Hebei 050091, China |
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| Abstract: | Objective To observe the clinical effects of Shenqi Qingdu Decoction on the protection of residual renal function (RRF), improvement of nutritional status and traditional Chinese medicine (TCM) syndromes on the basis of maintenance hemodialysis (MHD). Methods A total of 120 patients with chronic renal failure who underwent hemodialysis in Hebei Yiling Hospital from January 2017 to December 2018 were randomly divided into an observation group and a control group, with 60 cases in each group. The control group was treated with conventional MHD and basic medicine, while the observation group was treated with Shenqi Qingdu Decoction on the basis of the control group. RRF, daily urine volume, nutritional status and TCM syndrome scores were compared between the 2 groups before and after treatment. Results After treatment, the scores of TCM syndromes in the 2 groups were decreased than those before treatment (P<0.05), and the observation group was lower than that in the control group (P<0.05). After treatment, RRF and average daily urine volume in the 2 groups were decreased than those before treatment (P<0.05). RRF and average daily urine volume in the observation group were increased than those in the control group (P<0.05). After treatment, MAC, MAMC, TSF and BMI in the 2 groups were increased than those in the control group (P<0.05). After treatment, the nutritional status of patients in both groups was significantly improved (P<0.05). The number of patients with good nutrition in the observa tion group was significantly larger than that in the control group, and the number of patients with severe malnutri tion was significantly smaller than that in the control group (P<0.05). Conclusion Shenqi Qingdu Decoction combined with MDD and basic treatment can protect RRF of patients, improve nutritional status and TCM syndromes, and has definite curative effect, which is worthy of further clinical promotion. |
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| Keywords: | maintenance hemodialysis Shenqi Qingdu Decoction residual renal function TCM syndromes daily average urine volume nutritional status |
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