| 苓桂术甘汤加味治疗脾阳不足、痰饮内停型后循环缺血性眩晕的临床研究 |
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| 作者姓名： | 赵智儒 屈建峰 袁玉娇 |
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| 作者单位： | 北京市东城区第一人民医院, 北京 100075,北京市东城区第一人民医院, 北京 100075,北京市东城区第一人民医院, 北京 100075 |
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| 基金项目： | 北京市中医药科技发展基金项目（JJ2012-58）。 |
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| 摘 要： | 目的 探讨苓桂术甘汤加味治疗脾阳不足、痰饮内停型后循环缺血性眩晕患者的临床疗效。方法 将80例脾阳不足、痰饮内停型后循环缺血性眩晕患者采用随机数字表法分成治疗组和对照组，每组40例。治疗组患者服用苓桂术甘汤加味治疗，对照组患者给予前列地尔静滴治疗。治疗4周后，比较两组患者的眩晕症状评分、椎动脉及基底动脉血流动力学情况、血清超敏C-反应蛋白（hs-CRP）水平及药物的疗效。结果 治疗4周后，两组患者的眩晕症状评分及血清hs-CRP水平均较治疗前降低（P<0.05），且治疗组患者降低较对照组显著（P<0.05）；两组患者的收缩期末、舒张期末椎动脉及基底动脉的血流速度均较治疗前升高（P<0.05），且治疗组患者较对照组升高显著（P<0.05）；治疗组患者的总有效率（95.0%）高于对照组（80.0%）（P<0.05）。结论 苓桂术甘汤加味治疗脾阳不足、痰饮内停型后循环缺血性眩晕患者疗效较好，可明显改善患者的眩晕症状，促进患者的康复。
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| 关 键 词： | 后循环缺血 眩晕 苓桂术甘汤 超敏C-反应蛋白 血流动力学 |
| 收稿时间： | 2018/10/22 0:00:00 |
Clinical Study on Modified Linggui Zhugan Decoction in Treatment for Posterior Circulation Ischemic Vertigo with Spleen Yang Deficiency and Phlegm-fluid Retention |
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| Authors: | ZHAO Zhiru QU Jianfeng and YUAN Yujiao |
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| Institution: | Beijing Dongcheng District First People''s Hospital, Beijing 100075, China,Beijing Dongcheng District First People''s Hospital, Beijing 100075, China and Beijing Dongcheng District First People''s Hospital, Beijing 100075, China |
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| Abstract: | Objective To explore the clinical efficacy of modified Linggui Zhugan Decoction on patients with posterior circulation ischemic vertigo with spleen Yang deficiency and phlegm-fluid retention. Methods A total of 80 patients with posterior circulation ischemic vertigo with spleen Yang deficiency and phlegm-fluid retention were randomly divided into a treatment group and a control group, with 40 patients in each group. Patients of the treatment group were given the modified Linggui Zhugan Decoction orally, and the patients of the control group were given alprostadil drip. Vertigo symptom scores, hemodynamic situations of vertebral artery and basilar artery, serum hs-CRP levels and drug efficacy of the 2 groups were compared after 4 weeks of treatment. Results After 4 weeks of treatment, the vertigo symptom scores and serum hs-CRP levels of the 2 groups were lower than those before the treatment (P<0.05), and the decrease in the treatment group was more significant than that in the control group (P<0.05). The blood flow velocities of vertebral artery and basilar artery at the ends of systole and diastole in the 2 groups were higher than those before the treatment (P<0.05), and the increase in the treatment group was more significant than that in the control group (P<0.05). The total effective rate of the treatment group (95.0%) was higher than that of the control group (80.0%) (P<0.05). Conclusion The treatment of the modified Linggui Zhugan Decoction is effective in posterior circulation ischemic vertigo patients with spleen Yang deficiency and phlegm-fluid retention. It can obviously relieve the vertigo symptoms of patients, and promote the rehabilitation of patients. |
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| Keywords: | posterior circulation ischemia vertigo Linggui Zhugan Decoction hs-CRP hemodynamics |
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