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Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan
Authors:Kazuhiro Kawai  Hidetoshi Higuchi  Hidetomo Iwano  Akihiro Iwakuma  Ken Onda  Reiichiro Sato  Tomohito Hayashi  Hajime Nagahata  Toshio Oshida
Institution:1. Department of Animal Health 1, School of Veterinary Medicine, Azabu University, , Sagamihara, Japan;2. Animial Health Laboratory, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, , Ebetsu, Japan;3. Department of Veterinary Biochemistry, School of Veterinary Medicine, , Ebetsu, Japan;4. Zoetis Japan Inc., , Tokyo, Japan;5. National Institute of Animal Health, National Agriculture and Food Research Organization, , Sapporo, Japan
Abstract:Mycoplasma spp. are highly contagious pathogens and intramammary Mycoplasma infection is a serious issue for the dairy industry. As there is no effective vaccine for Mycoplasma infection, control depends on good husbandry and chemo‐antibiotic therapy. In this study, antimicrobial susceptibility of Mycoplasma strains recently isolated from cases of bovine mastitis in Japan was evaluated by minimum inhibitory concentration (MIC). All Mycoplasma bovis strains were sensitive to pirlimycin, danofloxacin and enrofloxacin, but not kanamycin, oxytetracycline, tilmicosin or tylosin. M. californicum and M. bovigenitalium strains were sensitive to pirlimycin, danofloxacin, enrofloxacin, oxytetracycline, tilmicosin and tylosin, but not to kanamycin. This is the first report to describe the MIC of major antimicrobial agents for Mycoplasma species isolated from bovine mastitis in Japan.
Keywords:antimicrobial agent  mastitis  minimum inhibitory concentration  Mycoplasma
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