| AA肉鸡生长过程中血液CD3+、CD4+和CD8+T淋巴细胞亚群的变化规律 |
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| 引用本文： | 孙国庆,王纯洁,赵怀平.AA肉鸡生长过程中血液CD3+、CD4+和CD8+T淋巴细胞亚群的变化规律[J].内蒙古农业科技,2007(3):59-62. |
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| 作者姓名： | 孙国庆 王纯洁 赵怀平 |
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| 作者单位： | 内蒙古农业大学,动物科学与医学学院,内蒙古,呼和浩特,010018 |
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| 摘 要： | 为了进一步了解AA肉鸡血液T淋巴细胞及其CD4 、CD8 亚群所占比例的变化规律及对免疫系统中的重要作用,使用流式细胞仪对1、3、5、7、14、21、28、35、42、的日龄AA肉鸡血液CD3 T淋巴细胞和CD4 、CD8 T细胞亚群比例进行检测.结果表明,1～5日龄CD3 T淋巴细胞含量逐渐升高,7日龄突然下降,14～21日龄急速升高,并达到最高峰后急速下降至28日龄,35～49日龄时相对趋于平稳状态;CD4 T细胞含量1～3日龄明显低于其余日龄,3～5日龄急速上升,7～14日龄增加缓慢,21日龄时达到最高峰后急速下降至28日龄,35～49日龄时基本趋于平稳状态;CD8 T细胞含量1～5日龄缓慢上升,5～7日龄急速下降后,再急速上升到14日龄,14～28日龄再下降,此后直至49日龄均在此水平上处于平稳状态.CD4 /CD8 比例:1～7日龄缓慢增加,7～14日龄比例急速下降至最低,14～21日龄时比例增加到最高峰后急速下降至28日龄,但比例数值高于前1～7日龄,28～49日龄比例趋于平稳状态.表明AA雏鸡在1～7日龄时其免疫功能逐渐提高,14日龄时细胞免疫功能明显减弱,这可能与CD8 T淋巴细胞含量高有关,21日龄时机体细胞免疫水平达最高状态,在28日龄后肉鸡细胞免疫功能基本保持稳定状态,但仍需要加强饲养管理.
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| 关 键 词： | AA肉鸡 血液 CD3 T淋巴细胞 CD4 T淋巴细胞 CD8 T淋巴细胞 |
| 文章编号： | 1007-0907(2007)03-0059-04 |
| 修稿时间： | 2007年3月17日 |
The Dynamic Changes of the Concentration of CD3+ cells and CD4+,CD8+ Subsets T Lymphocytes in Blood of Abor Aerec Flesh Chichen |
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| SUN Guo-qin,WANG Chun-jie,ZHAO Huai-ping.The Dynamic Changes of the Concentration of CD3+ cells and CD4+,CD8+ Subsets T Lymphocytes in Blood of Abor Aerec Flesh Chichen[J].Inner Mongolia Agricultural Science and Technology,2007(3):59-62. |
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| Authors: | SUN Guo-qin WANG Chun-jie ZHAO Huai-ping |
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| Abstract: | In order to verify the dynamic changes of T lymphocyte and its subsets in Abor Aerec flesh fowl.Lymphocytes were separated from blood of chickens.Then the concentration of CD4 and CD8 subsets of T cells and CD3 T cells were checked with flow cytometry machine in different old days,respectively.As the results: The concentration of CD3 T is in the highest level on 21 days old.But it was lower than others on7 days old.The concentration of CD4 T is in the highest level on 21 days old.But it was lower than others on1,3 days old.The concentration of CD8 T cell increased quickly on 1,3,5,14 days old.The highest level was on 14 days old.The ratios of CD4 /CD8 increased slowly from 1 to 7 days old,decreased on 14 days old.The highest level was on 21 days old.The others contain stable level.It showed that: The immune system of Abor Aerec flesh fowl became hyperfunction from 1 to 7days-old gradually,and it became hypofunction on 14 days old distinctly.The immunity was at highest on 21 days old then became steady after 28 days-old.It showed that the immune system almost maturated and advert to keep feeding. |
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| Keywords: | Abor Aerec flesh chicken Blood CD3 T cell CD4 T cell CD8 T cell |
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