Distribution of hepatitis B virus (HBV) genotypes among HBV carriers in Isparta |
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| Authors: | Kaya Selcuk Cetin Emel Sesli Aridogan Buket Cicioglu Onal Süleyman Demirci Mustafa |
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| Institution: | Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey. selcuk@med.sdu.edu.tr |
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| Abstract: | BACKGROUND: The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) genotypes in Isparta, Southwest of Turkey, as well as the clinical features and transmission route for patients with HBV infections. METHODS: Patients (n = 135) with HBV infection were included in the study. Epidemiological and clinical data were obtained. HBV genotypes were determined with a preS2 epitope ELISA kit. RESULTS: Although the HBV transmission route remained unidentified in 51.1% of the patients, blood contact was determined as the most common probable transmission route (38.5%). One hundred twenty-four (91.8%) of 135 samples, could be genotyped. One hundred fifteen (85.1%) were genotyped as type D/E, six (4.4%) were genotyped as type A, two (1.4%) were genotyped as type C, and one (0.7%) were genotyped as type F. CONCLUSION: Genotype D/E is determined as the predominant HBV genotype circulating in Isparta, Southwest of Turkey. No relationship between genotypes and disease severity and transmission route has been detected. |
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