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| 小鼠急性缺氧后心肌肥大细胞的变化 | |
| 引用本文： | 张书起,于洪川,魏智清,陈军红,陈吉利.小鼠急性缺氧后心肌肥大细胞的变化[J].农业科学研究,2006,27(2):38-41. |
| 作者姓名： | 张书起 于洪川 魏智清 陈军红 陈吉利 |
| 作者单位： | 1. 宁夏大学,农学院,宁夏,银川,750021 2. 宁夏大学,生命科学学院,宁夏,银川,750021 3. 宁夏医学院,基础部,宁夏,银川,750004 |
| 摘 要： | 应用组织化学方法对对照组、缺氧组、雌激素预处理缺氧组小鼠心肌肥大细胞的数量、活性及组化性质作了研究.结果表明,缺氧组小鼠肥大细胞和脱颗粒数目均极显著地高于同期对照组和雌激素预处理缺氧组(P<0.01),随着急性缺氧时间的延长,缺氧组小鼠肥大细胞和脱颗粒也呈直线上升趋势.雌激素预处理缺氧组小鼠的肥大细胞和脱颗粒极显著地低于同期缺氧组(P<0.01),而显著高于同期对照组(P<0.05).AB-S染色显示,心肌肥大细胞多数为黏膜肥大细胞,少数为结缔组织肥大细胞.试验结果为:肥大细胞参与急性缺氧造成心肌损伤的病理过程,雌激素对心肌缺氧损伤有保护作用. |
| 关 键 词： | 小鼠 急性缺氧 肥大细胞 雌激素 心肌 |
| 文章编号： | 1673-0747(2006)02-0038-04 |
| 收稿时间： | 2005-11-28 |
| 修稿时间： | 2005年11月28 |
The change of mice's cardiac mast cells after acute hypoxia |
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| Zhang Shuqi,Yu Hongchuan,Wei Zhiqing,Chen Junhong,Chen Jili.The change of mice''''s cardiac mast cells after acute hypoxia[J].Journal of Agricultural Sciences,2006,27(2):38-41. | |
| Authors: | Zhang Shuqi Yu Hongchuan Wei Zhiqing Chen Junhong Chen Jili |
| Institution: | 1. School of Agriculture, Ningxia University, Yinchuan 750021 China; 2. School of Life Sciences, Ning Xia University, Yinchuan 750021, China; 3. Base department, Medical College of Ningxia, Yinchuan 750004 ,China |
| Abstract: | By applying histochemical staining methods,the quantity,activation and histochemical property of the mice's cardiac mast cells were researched with the control group,hypoxia group and the hypoxia group with estrogen pretreatment.The results showed that the quantity of the mast cells and the degranules from the mast cells of hypoxia group were significantly higher than those of control group and the hypoxia group with estrogen pretreatment within the same period(P<0.01).As the period of acute hypoxia prolonged,the quantity of the mast cells and the degranules from the mast cells of hypoxia group increased in a straight line.The quantity of the mast cells and the granules from the mast cells of the hypoxia group with estrogen pretreatment were significantly lower than those of the hypoxia group and higher than those of control group within the same period.The AB-S dying showed that most of the cardiac mast cells were mucous mast cells and the rest were connective tissue mast cells.The conclusion was that mast cells took part in the pathological procedure which caused myocardium injury during acute anoxia.Estrogen had the protecting function to prevent myocardium anoxia injury. |
| Keywords: | mouse acute hypoxia mast cell estrogen myocardium |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |