Signalment and Clinical Complaints Initiating Hospital Admission,Methods of Diagnosis,and Pathological Findings Associated with Bovine Lymphosarcoma (112 Cases) |
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| Authors: | AJ Burton DV Nydam ED Long TJ Divers |
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| Abstract: | Background: Lymphosarcoma in adult cattle has multiple manifestations. Objective: To describe the signalment, clinical complaints, and tumor location, and to evaluate utility of diagnostic tests in cattle with lymphosarcoma. Animals: Adult cattle admitted to Cornell University between January 1980 and December 2008 with a definitive diagnosis of lymphosarcoma. Methods: Retrospective case study was conducted with a search of all medical records at Cornell University for cattle diagnosed with lymphosarcoma. Categorical data were analyzed with a Wilcoxon rank‐sum tests. Sensitivities of diagnostic tests were calculated. Results: There were 106 cows and 6 bulls (median age 5 years) examined for anorexia (34%), weight loss (16%), and fever (14%). The sensitivities of antemortem diagnostic tests performed were peripheral lymph node (PLN) wedge biopsy, 100%; surgical exploration and biopsy, 100%; pleurocentesis, 80%; pericardiocentesis, 67%; PLN fine‐needle aspirate, 41%; abdominocentesis, 33%; and cerebral spinal fluid tap, 19%. Median peripheral blood lymphocyte count was 4,900 cells/μL, 10% of cattle were leukemic and 25% had lymphocytosis according to the Bendixen Key. The most frequently identified tumor locations (% of cattle) were the heart (66%), abomasum (61%), uterus (38%), kidney (32%), and epidural space (26%). Conclusions and Clinical Importance: Predilection sites were similar to previously reports but we found a higher incidence of renal tumors and lower incidence of retrobulbar tumors. Knowledge of common clinical presentations, organ involvement, and sensitivities of diagnostic tests will aid informed decisions on the most appropriate tests and interpretation of their results in clinical cases of bovine lymphosarcoma. |
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| Keywords: | Bovine lymphosarcoma virus Cattle Necropsy |
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